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Textbook of Medicinal Chemistry Vol II de V Alagarsamy

Textbook of Medicinal Chemistry Vol II

Autor V Alagarsamy
en Limba Engleză Paperback – 14 mar 2009
Dr Alagarsamy's Textbook of Medicinal Chemistry is a much-awaited masterpiece in its arena. Targeted mainly to B. Pharm. students, this book will also be useful for M. Pharm. as well as M. Sc. organic chemistry and pharmaceutical chemistry students. It aims at eliminating the inadequacies in teaching and learning of medicinal chemistry by providing enormous information on all the topics in medicinal chemistry of synthetic drugs.
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Specificații

ISBN-13: 9788131221907
ISBN-10: 8131221903
Pagini: 548
Editura: Elsevier

Cuprins

Preface v
Acknowledgements vii
SECTION I Drugs Acting on Inflammation/Allergy 1
Chapter 1 Antihistamines 3
. Structure-Activity Relationship-H1 Receptor
Antagonists . Classification . Synthesis and Drug Profile
Chapter 2 Prostaglandins 46
. Functions of PGs . Biosynthesis . Synthesis
and Drug Profile
Chapter 3 Analgesics, Antipyretics, and NSAIDs 56
. Classification . SAR of Salicylates; Synthesis
and Drug Profile; SAR of p-Amino Phenol
Derivatives; SAR of 3,5-Pyrazolidine Diones;
SAR of Anthranilic Acid Derivatives;
SAR of Aryl Alkanoic Acid Derivatives;
SAR of Indole Acetic Acid Derivatives; SAR of Oxicams
SECTION II Drugs Acting on Respiratory System 107
Chapter 1 Expectorants and Antitussives 109
. Introduction to Respiratory System . Expectorants and
Antitussives . Classification . Synthesis and Drug Profile
Section III Drugs Acting on Digestive System 119
Chapter 1 Antiulcer Agents 121
. Classification . Synthesis and Drug
Profile . SAR of H2-Receptor Antagonists
Chapter 2 Antidiarrhoeals 137
. Synthesis and Drug Profile
SECTION IV Drugs Acting on Blood and Blood-Forming Organs 143
Chapter 1 Coagulants 145
. Classification . Anticoagulants;
Classification; Synthesis and Drug Profile
Chapter 2 Plasma Expanders 160
SECTION V Drugs Acting on Endocrine System 163
Chapter 1 Oral Hypogylcaemic Drugs 165
. Classification . Synthesis and Drug
Profile . SAR of Sulphonyl Ureas
Chapter 2 Steroids 192
. Steroid Nomenclature and Structure
. Progestogens . Oestrogens . Androgens and
Anabolic Agents
Chapter 3 Antithyroid Drugs 215
. Classification . Synthesis and Drug Profile
SECTION VI Chemotherapy 221
Chapter 1 History and Development of Chemotherapy 223
. Historical Background . Spectrum of
Activity of Chemotherapeutic Agents
Chapter 2 Antibacterial Sulphonamides 229
. SAR of Sulphonamides . Classification
. Synthesis and Drug Profile
Chapter 3 Quinolone Antibacterials 254
. Effective Antibacterial Quinolone
Derivatives . Synthesis and Drug Profile . SAR of
Quinolones
Chapter 4 Antibiotics 265
. Classification . Penicillins; Cephalosporins;
Amino Glycoside Antibiotics; Tetracyclins; Polypeptide
Antibiotics; Macrolide Antibiotics; Lincomycins; Other
Antibiotics
Chapter 5 Antitubercular Agents 331
. Synthesis and Drug Profile
Chapter 6 Antifungal Agents 344
. Classification . Synthesis and Drug Profile
Chapter 7 Antiviral Agents 364
. Introduction . Classification . Synthesis and Drug Profile
. SAR of Amantadine Analogues
Chapter 8 Antiamoebic Agents 401
. Classification of Amoebicides . Synthesis
and Drug Profile
Chapter 9 Antimalarials 409
. Life Cycle of Plasmodium . Classification
. Synthesis and Drug Profile . Structure-Activity
Relationship
Chapter 10 Anthelmintics 435
. Classification . Synthesis and Drug Profile
Chapter 11 Antineoplastic Agents 455
. Classification . Synthesis and Drug Profile
Chapter 12 Antileprotic Drugs 511
. Classification . Synthesis and Drug Profile