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Thalassemia, An Issue of Hematology/Oncology Clinics of North America de Edward J. BenzJr

Thalassemia, An Issue of Hematology/Oncology Clinics of North America: The Clinics: Internal Medicine, cartea 37-2

Editat de Edward J. BenzJr, Vijay G. Sankaran
en Limba Engleză Hardback – 20 mar 2023
In this issue of Hematology/Oncology Clinics, guest editors Drs. Edward J. Benz, Jr. and Vijay G. Sankaran bring their considerable expertise to the topic of Thalassemia. Top experts in the field provide an overview of the history, epidemiology, pathogenic mechanisms, and clinical management of the thalassemia syndromes.
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Specificații

ISBN-13: 9780443183201
ISBN-10: 0443183201
Pagini: 240
Dimensiuni: 152 x 229 x 20 mm
Greutate: 0.56 kg
Editura: Elsevier
Seria The Clinics: Internal Medicine

Cuprins

Introduction to the Thalassemia Syndromes: Molecular Medicine's Index Case
The Need for Translational Epidemiology in Beta Thalassemia Syndromes:A Thalassemia International Federation Perspective
Molecular Basis and Genetic Modifiers of Thalassemia
Fetal Hemoglobin Regulation in Beta-Thalassemia
Clinical Classification, Screening, and Diagnosis in Beta-Thalassemia and Hemoglobin E/Beta-Thalassemia
The Clinical Phenotypes of Alpha Thalassemia
Pathogenic Mechanisms in Thalassemia I: Ineffective Erythropoiesis and Hypercoagulability
Pathogenic Mechanisms in Thalassemia II: Iron Overload
Clinical Complications and Their Management
Clinical Challenges with Iron Chelation in Beta Thalassemia
Fertility and Pregnancy in Women with Transfusion-Dependent Thalassemia
Hematopoietic Stem Cell Transplantation in Thalassemia
Gene Therapy and Gene Editing for b-Thalassemia
Emerging Therapies in b-Thalassemia