Georgia Peachy Archer Laliberte has almost gotten her life under control. Peachy, her husband Beau, and their two rambunctious sons live on the family farm in a small town in Canada, just across the border from the U.S.. Their closest neighbor is Peachy's draft-dodging hairdresser father, Lou, who lives in a trailer on their land. Although her son Sam has epilepsy, Peachy, Beau, and Lou have worked out a successful system to care for him and maintain as normal a family life as possible, and Peachy's status as a superhuman caregiver has its own rewards.
When her life on the farm isn't quite enough, Peachy can always live vicariously through her glamorous, New York City-dwelling sister, Beth. Thin, successful, and passionate Beth has clawed her way to the top, stepping on anyone it takes to get there -- including, every so often, her younger sister. Still, Peachy and Beth are close, and they support each other through crises of all kinds.
They support each other, that is, until Beth decides to sleep with Peachy's husband Beau -- who just happens to be Beth's ex-boyfriend. Furious, Peachy decides to go to New York City -- alone -- and leaves Beth home to care for her family. As she spends a terrified, exciting weekend alone in the middle of Beth's life, Peachy must confront questions of love, loyalty, and family to find her way back home.