When a SpyCo secret agent, code-named Willy, is mysteriously killed on a deserted road during the late hours of the night, things begin falling apart for SpyCo's chief executive, Mr. J. Carlton Moore. A briefcase containing highly classified information, which was assigned to Willy's care, disappears in the confusion and leaves the future of the United States' war on terror in doubt. With the terrorist group Scorpion being suspected of possessing the missing briefcase and vital information somehow leaking from the most secure SpyCo meetings, Moore calls on crack covert operative James Reagan Burke. Burke's job? Recover the briefcase and unearth the mole. Not an easy task to begin with, but when Burke's first full day on the job is begun with two assassination attempts in close succession, he begins to suspect that perhaps it is going to be even more difficult than he had anticipated. Thrown together into an unlikely team comprised of a former flame and a Grecian body-builder, and seeing shadowy pursuers at every turn, Burke must decide whom he can trust.