Nickel is an essential element in many biochemical processes and there has been significant recent research into understanding the role this transition element plays. This book discusses a range of key topics in this field including the coordination chemistry of nickel-containing biomolecules, current theories on nickel-containing enzymes and the transport, storage and transcriptional regulation of nickel in biological systems. An essential text for biochemists, biologists and medicinal chemists, this book provides a comprehensive review of the latest findings in nickel biology and chemistry.