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The Biology of Germinal Centers in Lymphoid Tissue

Editat de G. Jeanette Thorbecke, Vincent K. Tsiagbe
en Limba Engleză Paperback – 22 ian 2013
This book meets the demand of a recent surge of interest in germinal centers, the foci of antigen-induced, rapidly proliferating B lymphocytes, representing sites in mammalian lymphoid tissue where memory B cells are generated. Various aspects of the generation of germinal centers, the somatic hypermutation process and the cellular interactions involved in the selection process are discussed in detail. A chapter on germinal center-derived lymphomas completes the treatment.
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Specificații

ISBN-13: 9783662131435
ISBN-10: 3662131439
Pagini: 256
Ilustrații: XI, 241 p. 21 illus., 6 illus. in color.
Dimensiuni: 155 x 235 x 13 mm
Greutate: 0.36 kg
Ediția:Softcover reprint of the original 1st ed. 1998
Editura: Springer Berlin, Heidelberg
Colecția Springer
Locul publicării:Berlin, Heidelberg, Germany

Public țintă

Research

Cuprins

1. Overview of Germinal Center Function and Structure in Normal and Genetically Engineered Mice.- 2. The Germinal Center Reaction: Influence of FDC Function in Normal, Aged, and Retrovirus Infected Hosts.- 3. T and B Lymphocytes in Germinal Centers.- 4. Somatic Hypermutation of Immunoglobulin Genes.- 5. Germinal Center Derived Lymphomas in Humans and Mice.- Color Figures.

Caracteristici

The latest results on the research in mammalian lymphoid tissue and lymphomas.