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The Blood-Brain Barrier and Its Microenvironment: Basic Physiology to Neurological Disease

Editat de Elga de Vries, Alexandre Prat
en Limba Engleză Hardback – 24 aug 2005
This reference analyzes the cellular and molecular biology and mechanisms of the blood-brain barrier (BBB) and presents the most recent studies on the role of the BBB in the development and initiation of a wide range of physiological and pathological conditions affecting the central nervous system.
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Specificații

ISBN-13: 9780849398926
ISBN-10: 0849398924
Pagini: 544
Ilustrații: 46 black & white illustrations, 17 black & white tables, 18 black & white halftones
Dimensiuni: 152 x 229 x 30 mm
Greutate: 0.84 kg
Ediția:1
Editura: CRC Press
Colecția CRC Press

Public țintă

Professional

Cuprins

Development of the Blood-Brain Barrier. Blood-Brain Barrier Genomics and Proteomics. Tight Junctions of the Blood-Brain Barrier. Trophic Factors and Cerebrovascular Regulation. Neuronal Influence at the BBB and Local Control of Microcirculation. The Transport Systems of the Blood-Brain Barrier. Drug Delivery Through the BBB: Non Viral Vectors. Immune Functions of Brain Endothelial Cells. T Cell Migration Across the Blood-Brain Barrier in CNS Inflammatory Diseases. Endothelial ICAM-1 Mediated Signalling and Its Role During Lymphocyte Migration into the CNS Parenchyma. Monocyte Migration across the BBB. Cerebral Perivascular Macrophages and the Blood-Brain Barrier. Chemokines at the Blood-Brain Barrier. Matrix Metalloproteinase and Proteolytic Opening of the Blood-Brain Carrier in Neuroinflammation. Endothelial cells, Extracellular Matrix and Astocytes: Interplay for Managing the Blood-Brain Barrier. Molecular Modulation of the Blood-Brain Barrier During Stroke. Apolipoprotein E, the Blood-Brain Barrier and Alzheimer's Disease. Techniques for Measuring the Blood-Brain Barrier Integrity. Influence of Brain Trauma on Blood-Brain Barrier Properties. Non-HIV Viral Interaction with the BBB

Descriere

This reference analyzes the cellular and molecular biology and mechanisms of the blood-brain barrier (BBB) and presents the most recent studies on the role of the BBB in the development and initiation of a wide range of physiological and pathological conditions affecting the central nervous system.