The overarching question that this book's 17 chapters address is: How can psychotherapists best help in relieving their clients' suffering? The underlying theme of how to facilitate another human being's return to a healthy and fulfilling life has been addressed in many ways by philosophers, psychologists, physicians, theologians, poets, artists, and others for millennia. This book is about this theme. In the context of clinical practice, this aspiration is examined from a variety of innovative approaches that includes collaborative and digital assessment, neuroscience, neo-Kleinian therapy, intuition, holistic therapies, transpersonal psychology, mindfulness training, Ayurvedic medicine, and parapsychology. Topics addressed include the grieving process, addictive behaviors, clinical supervision, pain and stress, living with disability, psychosis, child abuse, anomalous experiences, anorexia, non-epileptic seizures, and the application of phenomenological research methodology.