Housewife assassin Donna Stone must be more than just ready for her close-up if she's to stop a terrorist cell intent on exposing the United States' vulnerability to an attack on American soil. The only intel provided to Donna, Jack, and their mission team at Acme Industries is that it will take place during a live broadcast of a reality TV show. And wouldn't you know it: each of the other housewife contestants has dirty little secrets that make them and their husbands very probable Persons of Interest. So, who is the terrorist who wants to hold these celebrity housewives hostage-and worse yet, kill them off in front of their adoring fans?