Non-response in sample surveys can have serious consequences on the accuracy of survey results. This study shows how high response rates can be achieved, even in the Netherlands, a country notorious for its low response rates. As an introduction, an overview of groups that generally have low response rates and the possible causes of their lack of response is presented. The emphasis is on non-response bias that occurs when non-response behavior and survey outcomes are correlated, independent of background characteristics. The Hunt for the Last Respondent will be of interest to survey methodologists, market researchers, survey sponsors, and survey statisticians, as well as anyone interested in survey quality.