Based on Native American myths and legends, the Little People is the story of a young boy's magical adventure. After moving to a new town due to his mother's illness, a boy named Adam discovers the last tribe of small magical people called Nuh-na-yie, along with their ancient animal spirit friends, living in the forest behind his new home. As the white man began to spread across the land, the Nuh-na-yie's magic faded, so they decided to leave our world. Before they could all magically cross over to a new home in another world, they were attacked by Uktena, an evil black serpent with feathered wings and sharp horns. Uktena lead his minions, the Nunnehi, to try and capture the Nuh-na-yie to take from them the magical key of crossing. During the battle, some of the Little People and their animal spirit friends were cut off from the rest of their tribe. Having lost the key of crossing during the conflict, they were forced to remain in our world along with Uktena. Adam discovers, through his Native American heritage, that he has the key. An ancient object that has been with his family for generations. With the help of his sister Abi and Mr. Josh, their next door neighbor, Adam tries to protect his family and help his new friends to defeat Uktena and find the place of crossing so they can rejoin their people.