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The Microtubule Cytoskeleton: Organisation, Function and Role in Disease

Editat de Jens Lüders
en Limba Engleză Paperback – 19 apr 2016
This book provides an overview on the organization andfunction of the microtubule cytoskeleton, which is essential to many cellularprocesses and profoundly linked to a range of human diseases.Covering basic concepts as well as molecular details, the book discusses howmicrotubules are nucleated and organized into ordered arrays, at different cellcycle stages and in distinct cell types. In addition, the book highlights howdefects in the microtubule cytoskeleton are linked to diseases such asneurodevelopmental disorders.
The book is intended for students, graduates and moresenior researchers in cell and developmental biology as well as for medicaldoctors.
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Specificații

ISBN-13: 9783709119013
ISBN-10: 3709119014
Pagini: 189
Ilustrații: VII, 189 p. 20 illus., 14 illus. in color.
Dimensiuni: 155 x 235 x 11 mm
Greutate: 0.4 kg
Ediția:1st ed. 2016
Editura: SPRINGER VIENNA
Colecția Springer
Locul publicării:Vienna, Austria

Cuprins

Part 1. Organization of the microtubule cytoskeleton Microtubule nucleators.- Microtubule regulators.- Microtubule organizing centers. Part 2. Assembly, maintenance and function of microtubule-based organellesCentrioles/basal bodies.- Centrosomes.- Cilia. Part 3. The microtubule cytoskeleton and disease Microtubule-based.- Centrosome-based.- Ciliopathies.​

Notă biografică

Jens Lüders, PhD, is leading the Microtubule organization group at the Institute for Research in Biomedicine (IRB), in Barcelona, Spain. 



Textul de pe ultima copertă

This book provides an overview on the organization and function of the microtubule cytoskeleton, which is essential to many cellular processes and profoundly linked to a range of human diseases. Covering basic concepts as well as molecular details, the book discusses how microtubules are nucleated and organized into ordered arrays, at different cell cycle stages and in distinct cell types. In addition, the book highlights how defects in the microtubule cytoskeleton are linked to diseases such as neurodevelopmental disorders.
The book is intended for students, graduates and more senior researchers in cell and developmental biology as well as for medical doctors.

Caracteristici

Most comprehensive work on the biology and function of microtubules on the market Treats basic mechanisms and organization of the microtubule cytoskeleton as well its involvement in disease Describes function, maintenance and biogenesis of microtubules based organelles Includes supplementary material: sn.pub/extras