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The Nitrile Imine 1,3-Dipole: Properties, Reactivity and Applications de Craig Jamieson

The Nitrile Imine 1,3-Dipole: Properties, Reactivity and Applications

Autor Craig Jamieson, Keith Livingstone
en Limba Engleză Hardback – 26 mar 2020
This book provides a comprehensive overview of the nitrilimine 1,3-dipole, from its initial discovery in 1959 to the most recent publications. Covering topics such as the core properties of the dipole and the various methods of synthesis available, it particularly highlights the diverse reactivity profile of the nitrilimine and its numerous applications in bioorthogonal and materials chemistry. The book is of interest to academic and industrial researchers working in this area and to those new to the field.
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Specificații

ISBN-13: 9783030434809
ISBN-10: 303043480X
Pagini: 152
Ilustrații: XI, 152 p. 218 illus., 120 illus. in color.
Dimensiuni: 155 x 235 mm
Greutate: 0.41 kg
Ediția:1st ed. 2020
Editura: Springer International Publishing
Colecția Springer
Locul publicării:Cham, Switzerland

Cuprins

Chapter 1 - Nitrile Imines and Their Properties.- Chapter 2 - The Generation of Nitrile Imine Derivatives.- Chapter 3 - The Reactivity of Nitrile Imines.- Chapter 4 - Applications of Nitrile Imine Derivatives.- Chapter 5 - Conclusions.

Notă biografică

Craig Jamieson earned his B.Sc. (Hons) in Chemistry at the University of Glasgow in 1996. He pursued his Ph.D. studies under Professor R Ramage at the University of Edinburgh (1999). Following postdoctoral research under the supervision of Professor S V Ley at the University of Cambridge, in 2001 he was appointed as a Principal Scientist in GlaxoSmithKline's Discovery Medicinal Chemistry group, working on a range of exploratory medicinal chemistry programmes. In 2004, Dr Jamieson joined Organon Laboratories (later Merck Research Labs) as a Group Leader in the Medicinal Chemistry Department, with responsibility for hit to clinical candidate optimisation. In August 2010, he was appointed as a John Anderson Research Lecturer in Chemical Biology, based in the Department of Pure and Applied Chemistry at the University of Strathclyde.

Keith Livingstone completed his M.Chem in Chemistry with Drug Discovery at the University of Strathclyde (2016) under the supervision of Dr Craig Jamieson. Keith remained at Strathclyde and is currently in the final year of his doctoral studies with Dr Jamieson, which have also included two short research secondments at GlaxoSmithKline Medicines Research Centre Stevenage, and with Prof Ryan Gilmour at the Westfälische Wilhelms-Universität Münster.


Textul de pe ultima copertă

This book provides a comprehensive overview of the nitrilimine 1,3-dipole, from its initial discovery in 1959 to the most recent publications. Covering topics such as the core properties of the dipole and the various methods of synthesis available, it particularly highlights the diverse reactivity profile of the nitrilimine and its numerous applications in bioorthogonal and materials chemistry. The book is of interest to academic and industrial researchers working in this area and to those new to the field.

Caracteristici

Provides a comprehensive overview of nitrilimine chemistry from discovery to the present day Is accessible to academic researchers, industry professionals and students Highlights the diverse applications of nitrilimines