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The Origin and Development of Genetic Therapies: From Magic and Superstition to Molecular Genetics and the Human Genome

Autor Theodore Friedmann
en Limba Engleză Paperback – 2 oct 2025
From the discoveries of the principles of genetic inheritance in the 19th century to the development of the concepts of human molecular genetic disease in the 20th century, the treatment of human disease has been transformed from a focus on symptoms to the goal of correcting underlying genetic defects which are the cause of many human diseases. Here, Theodore Friedmann shows that this scientific revolution in medicine compares in importance to Copernicus's demonstration of the sun-centered order of the planetary system, the 18th and 19th century discoveries of the cellular structure of living systems, germ theory of disease, the invention of anaesthesia, and the discovery that genetic information is stored and transmitted by DNA. The Origin and Development of Genetic Therapies explores the origins and early developmental history of the medical field of gene therapy. Friedmann examines the early failures and increasingly promising clinical "successes" for this new approach to cure genetic disease and explores how the concepts of gene therapy can affect human hereditary and human evolution.
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Specificații

ISBN-13: 9780197689974
ISBN-10: 0197689973
Pagini: 216
Ilustrații: 113 halftones
Dimensiuni: 156 x 235 mm
Editura: Oxford University Press
Colecția OUP USA
Locul publicării:New York, United States

Notă biografică

Theodore Friedmann completed his medical training at the University of Pennsylvania, and clinical training in Pediatrics at the Boston Children's Hospital. He was awarded postdoctoral fellowships at the universities of Cambridge and Oxford, the U.S. National Institutes of Health, and the Salk Institute. In 1971, he joined the pediatric faculty of the School of Medicine at the University of California San Diego where he is currently affiliated as Emeritus Professor of Pediatrics.