The Osteoporosis Primer
Editat de Janet E. Henderson, David Goltzmanen Limba Engleză Paperback – 23 aug 2000
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Specificații
ISBN-13: 9780521644464
ISBN-10: 0521644461
Pagini: 388
Ilustrații: 50 b/w illus. 12 tables
Dimensiuni: 170 x 244 x 20 mm
Greutate: 0.75 kg
Editura: Cambridge University Press
Colecția Cambridge University Press
Locul publicării:Cambridge, United Kingdom
ISBN-10: 0521644461
Pagini: 388
Ilustrații: 50 b/w illus. 12 tables
Dimensiuni: 170 x 244 x 20 mm
Greutate: 0.75 kg
Editura: Cambridge University Press
Colecția Cambridge University Press
Locul publicării:Cambridge, United Kingdom
Cuprins
Preface Janet E. Henderson and David Goltzman; Part I. Molecular and Cellular Environment of Bone: 1. Endochondral bone formation and development in the axial and appendicular skeletaon A. Robin Poole, Sheila Laverty and Fackson Mwale; 2. The role of osteoblasts Jane E. Aubin; 3. Osteoclasts: characteristics and regulation of formation and activity Johan Heersche and Morris F. Manolson; 4. Bone matrix proteins Marc D. McKee and Jaro Sodek; 5. Local regulators of bone turnover Lawrence J. Fraher and Patricia H. Watson; 6. The PTH/PTHrP system and calcium homeostasis Geoffrey N. Hendy; 7. Vitamin D metabolism Marielle Gascon-Barre; 8. Sodium-dependent phosphate transport in kidney, bone and intestine Harriet S. Tenenhouse; Part II. Determinants of Peak Bone Mass: 9. Molecular genetic analysis of growth factor signalling in bone Janet E. Henderson and David Goltzman; 10. Genetic determinants of osteoporosis Milan S. Patel, Laurence A. Rubin and David E. C. Cole; 11. Non-genetic determinants of peak bone mass Velimir Matkovic and John D. Landoll; 12. Bone mineral acquisition during childhood and adolescence: physical exercise as a preventative measure Heather A. McKay and Karim M. Khan; 13. Osteoporosis in children Frank Rauch and Francis H. Glorieux; Part III. Pathophysiology of the Aging Skeleton: 14. Consequences of alterations in bone remodeling Karen Prestwood and Lawrence G. Raisz; 15. The role of parathyroid hormone and hyperparathyroidism in osteoporosis Pierre D'Amour; 16. Senile osteoporosis Patrick M. Doran and Sundeep Khosla; Part IV. Clinical Aspects of Osteoporosis; 17. Epidemiology Jaques Brown; 18. Biochemical markers of bone turnover David Hanley; 19. Radiologic assessment of osteoporosis Jaqueline C. Hodge; 20. Bone mineral density measurements Paul D. Miller and Carol Zapalowski; 21. Hormone replacement therapy Jonathan D. Adachi and Alexandra Papaioannou; 22. Selective estrogen receptor modulators Felicia Cosman and Robert Lindsay; 23. Bisphosphonate therapy of osteoporosis Fred Singer and Payam Minoofar; 24. The action of fluoride on bone Marc D. Grynpas, D. Chachra and H. Limeback; 25. PTH peptides as anabolic agents in bone Anthony B. Hodsman; 26. Vitamin D and Vitamin D analogs as therapeutic agents Richard Kremer.
Recenzii
'I really enjoyed tying together the cell biology and the basis of the current treatments and potential therapeutic interventions. I found that I knew a lot more about bone cell physiology, bone turnover and cell signalling by the end of the section. … The book succeeds as an introductory text on metabolic bone disease and provides insight into the complexity of the subject without becoming overwhelming.' Gerontology
'A clearly written and updated text … on a topic of increasing interest.' Journal of Pediatric Endocrinology and Metabolism
'This is a concise yet comprehensive synopsis of bone developments and skeletal homeostasis.' Aslib Book Guide
'A clearly written and updated text … on a topic of increasing interest.' Journal of Pediatric Endocrinology and Metabolism
'This is a concise yet comprehensive synopsis of bone developments and skeletal homeostasis.' Aslib Book Guide
Descriere
The Osteoporosis Primer provides an excellent introduction that relates the clinical presentation of osteoporosis to its molecular biochemical basis, and reviews therapeutic options.