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The Prostate Cancer Dilemma: Selecting Patients for Active Surveillance, Focal Ablation and Definitive Therapy

Editat de Nelson N. Stone, E. David Crawford
en Limba Engleză Hardback – 27 oct 2015
This text provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for clinicians, surgeons and researchers with an interest in early prostate cancer. The book reviews new data about genetic markers, transperineal mapping biopsy and mpMRI, how to apply each of these technologies in patients with elevated PSA, when a prior prostate biopsy performed by the standard TRUS method is negative and in cases where low risk disease is already diagnosed, how to differentiate those men who might harbor more aggressive disease from those who do not. Over 75% of newly diagnosed prostate cancer meets the criteria for low risk disease which has created a dilemma for both patients and clinicians. Active surveillance programs have been initiated and are reviewed. How the new technologies impact surveillance programs is addressed. Clinical stage designation is updated and a new intra-prostatic staging system is discussed. Prostate biopsy techniques utilizing transrectal ultrasound, transperineal mapping, elastography and mpMRI are compared. Finally, utilization of this new technology in the application of focal therapy is reviewed.
The Prostate Cancer Dilemma will serve as a very useful resource for physicians and researchers dealing with, and interested in this challenging malignancy. Chapters are written by experts in their fields and include the most up to date scientific and clinical information as well as links to procedural video content. 
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Specificații

ISBN-13: 9783319214849
ISBN-10: 3319214845
Pagini: 310
Ilustrații: XIV, 206 p. 55 illus., 49 illus. in color.
Dimensiuni: 155 x 235 x 17 mm
Greutate: 0.58 kg
Ediția:1st ed. 2016
Editura: Springer International Publishing
Colecția Springer
Locul publicării:Cham, Switzerland

Public țintă

Professional/practitioner

Cuprins

Part One: Diagnosis.- History of PSA, from Detection to Over Diagnosis.- Pathology of Prostate Cancer: What has Changed in the Last 30 years?- Clinical Risk Prediction Tools for Prostate Cancer: TMN to CAPRA-Should Risk be Re-defined?- TRUS Biopsy: Is There Still a Role?- Transperineal Biopsy Technique.- 3D Biopsy: A New Method to Diagnose Prostate Cancer.- Elastography: Can it Improve Prostate Biopsy Results?- Multi parametric MRI of the Prostate as a Tool for Prostate Cancer Detection.- Genomic Markers.- Part Two: Treatment.- Current Status of Clinical Trials in Active Surveillance.- Focused targeted Therapy in Prostate Cancer.- Technologies and Methods in Primary Ablation with Focal Therapy.- Multi parametric MRI (mpMRI)-Guided Focal Therapy.- Conclusions.

Recenzii

“The book will be of interest to both experiencedpractitioners and trainees in urology, radiation oncology, medical oncology,and interventional radiology. … This is an outstanding, succinct, yet thoroughoverview of current and leading-edge approaches to the diagnosis and managementof low-risk prostate cancer. This should be a valuable resource for those whoassist in the care of men with this common presentation of prostate cancer.” (MarkD. Hurwitz, Doody’s Book Reviews, February, 2016)

Notă biografică

Nelson N. Stone, MD.
Professor of Urology and Radiation Oncology
Department of Urology
The Icahn School of Medicine at Mount Sinai
New York, NY
USA
E. David Crawford, MD
Professor of Urology/Surgery and Radiation Oncology
University of Colorado
Denver, Aurora, CO 
USA

Textul de pe ultima copertă

This comprehensive text provides a complete description of the newest technologies to diagnose and manage the most common prostate cancer diagnosed today: low risk disease. The book reviews new data about genetic markers, transperineal mapping biopsy and mpMRI, how to apply each of these technologies in patients with elevated PSA, when a prior prostate biopsy performed by the standard TRUS method is negative, and, in cases where low risk disease is already diagnosed, how to differentiate those men who might harbor more aggressive disease from those who do not. Over 75% of newly diagnosed prostate cancer meets the criteria for low risk disease which has created a dilemma for both patients and clinicians because of the inaccuracy of the standard TRUS biopsy method. Active surveillance programs have been initiated and are reviewed. How the new technologies impact surveillance programs are addressed. Clinical stage designation is updated and a new intra-prostatic staging system is discussed. Prostate biopsy techniques utilizing transrectal ultrasound, transperineal mapping, elastography and mpMRI are compared. Finally, utilization of these new technologies in the application of focal therapy is reviewed.      
The Prostate Cancer Dilemma will serve as a valuable resource for clinicians, surgeons and researchers with an interest in early prostate cancer. Chapters are written by experts in their fields and include the most up-to-date scientific and clinical information as well as links to procedural video content.

Caracteristici

Written by experts in their fields Provides links to procedural video content Richly illustrated with color photographs, illustrations and tables