The Role of the Mitochondria in Neural Degeneration: Hot Topics in Physiology
Autor Xin Qien Limba Engleză Hardback – iun 2025
- Examines the role of mitochondria in neuronal function and survival
- Presents the latest findings on mitochondrial dysfunction, along with dynamics in neurodegenerative diseases
- Considers the impact of mitochondrial intercellular connections on neuronal health
- Discusses potential therapeutic options and the latest advances in mitochondrial medicine for the treatment of mitochondrial impairment
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Specificații
ISBN-13: 9780443217579
ISBN-10: 0443217572
Pagini: 400
Dimensiuni: 191 x 235 mm
Editura: ELSEVIER SCIENCE
Seria Hot Topics in Physiology
ISBN-10: 0443217572
Pagini: 400
Dimensiuni: 191 x 235 mm
Editura: ELSEVIER SCIENCE
Seria Hot Topics in Physiology
Cuprins
Section I Introduction to Mitochondria 1. A background introduction on mitochondria 2. Mitochondrial function in neuronal function and survival Section II Impairment of mitochondrial quality control: causes and effects? 3. Introduction to the effects of mitochondrial quality control impairment on cell fate 4. Mitochondrial dynamics in neurodegenerative diseases 5. Mitochondrial proteostasis in neuronal degeneration 6. Mitophagy and autophagy during neuronal degeneration 7. Mitochondrial transportation and neurodegenerative disorders 8. mtDNA integrity and neuronal degeneration Section III Impact of mitochondrial intercellular connections on neuronal health 9. Introduction to the effects of mitochondrial intercellular connection impairment on cellular function 10. Mitochondria-associated ER Membrane in neurodegenerative diseases 11. Mitochondria-cytoskeleton interface and neuronal degeneration 12. Mitochondria, inflammasome and immune response in neurological disorders 13. Mitochondria-synapses communication during neuronal degeneration Section IV Potential therapeutic strategy targeting mitochondria 14. Introduction of current advances in "mitochondrial medicine" for the treatment of human diseases 15. Mitochondrial genome editing and neurological disorders 16. Mitochondrial transplantation to reduce neuronal impairment 17. Development of mitochondria-targeting small molecules/biologics to treat neurological disorders 18. Summary and Conclusions