In the small village of Santa Cruz, located on the Island of Flores in the north Atlantic sea, an Azorean fisherman, Joaquin Miguel Salvador, makes the biggest decision of his life. He will leave Portugal's Azores islands and journey to America to find another Santa Cruz--this one in California. He dreams of making a better life for his wife, himself, and the son he longs to have. Trying five times to become a father to the son he so desperately wants, Miguel is left in disbelief at God's decision each time to send him a daughter. Sharing her father's strong Azorean heritage, each daughter follows her own path in life: some leading to joy, others to tragedy and sadness. Miguel, in a vain effort to keep his daughters close to home, bequeaths them shares in a parcel of land called Bonny Doon. The daughters find ways to use their land to pursue their dreams in ways their father could never have imagined. Also, unbeknownst to Miguel, a villain lurks within his Azorean genes, emerging as the devastating illness, Joseph's Disease, causing pain, suffering and even death to his loved ones. "The Six Daughters of Joaquin Miguel Salvador" is one family's story of love and dreams: some fulfilled, others denied.