The Subcommissural Organ: An Ependymal Brain Gland

I. Historical Reflections.- Ernst Reissner (1824–1878): Anatomist of the “Membrane” and “Fiber” (With 1 Figure).- Helmut Hofer (1912–1989) and the Concept of the Circumventricular Organs (With 1 Figure).- Historical Landmarks in the Investigation of the Subcommissural Organ and Reissner’s Fiber (With 1 Figure).- II. Phylogeny and Ontogeny.- Phylogenetic and Conceptual Aspects of the Subcommissural Organ (With 3 Figures).- Reissner’s Fiber Mechanisms: Some Common Denominators (With 3 Figures).- Ontogenetic Development of the Subcommissural Organ with Reference to the Flexural Organ (With 2 Figures).- Developmental Aspects of the Subcommissural Organ: An Approach Using Lectins and Monoclonal Antibodies (With 5 Figures).- The Subcommissural Organ and Ontogenetic Development of the Brain (With 5 Figures).- III. Biochemistry.- Protein Glycosylation in Mammalian Cells (With 3 Figures).- Partial Characterization of the Secretory Products of the Subcommissural Organ (With 3 Figures and 1 Table).- Biochemical and Immunochemical Analysis of Specific Compounds in the Subcommissural Organ of the Bovine and Chick (With 4 Figures and 3 Tables).- Immunochemical Analysis of the Dogfish Subcommissural Organ (With 2 Figures and 1 Table).- IV. Secretory Process, Including Model Systems.- Dynamic Aspects of the Secretory Process in the Amphibian Subcommissural Organ.- Evidence for the Release of CSF-Soluble Secretory Material from the Subcommissural Organ, with Particular Reference to the Situation in the Human (With 3 Figures).- The Subcommissural Organ In Vitro (With 2 Figures).- V. Relation to Other Circumventricular Organs: Conceptual Aspects.- Circumventricular Organs and Modulation in the Midsagittal Plane of the Brain (With 1 Figure and 1 Table).- Blood- and Cerebrospinal Fluid-Dominated Compartments of the Rat Brain (With 1 Figure).- VI. Neural Inputs.- The Subcommissural Organ of the Rat: An In Vivo Model of Neuron-Glia Interactions (With 2 Figures and 1 Table).- Neural Inputs to the Subcommissural Organ (With 2 Figures).- Impairment of the Serotoninergic Innervation of the Rat Subcommissural Organ after Early Postnatal X-Irradiation of the Brain Stem (With 2 Figures).- Immunocytochemistry of Neuropeptides and Neuropeptide Receptors in the Subcommissural Organ of the Rat (With 10 Figures).- VII. Connections with Other Brain Structures.- Relationships Between the Subcommissural Organ and the Pineal Complex (With 2 Figures).- The Goldfish Subcommissural Organ Is Not Innervated by Fibers of the Pineal Tract (With 2 Figures).- Immunochemical Relationships Between the Subcommissural Organ and Hypothalamic Neurons (With 6 Figures and 1 Table).- VIII. Physiology of the Cerebrospinal Fluid.- Cerebrospinal Fluid Secretion: The Transport of Fluid and Electrolytes by the Choroid Plexus (With 4 Figures).- Physiology of Cerebrospinal Fluid Circulation: Amphibians, Mammals, and Hydrocephalus (With 6 Figures and 1 Table).- IX. Experimental Aspects.- Effects of Hibernation and Hypothermia on the Secretory Activity of the Subcommissural Organ (With 3 Figures).- The Subcommissural Organ: Immunohistochemistry and Potential Relations to Salt/Water Balance (With 6 Figures and 1 Table).- Immunological Blockade of the Subcommissural Organ — Reissner’s Fiber Complex (With 6 Figures).- The Effect of Immunological Blockade of Reissner’s Fiber Formation on the Circulation of Cerebrospinal Fluid Along the Central Canal of the Rat Spinal Cord (With 4 Figures).- X. Discussion Sessions (With 3 Figures).- I Signal Pathways.- II Cell Biology and Biochemistry.- III Functional Aspects I.- IV Functional Aspects II.