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The Trajectory of Discovery: What Determines the Rate and Direction of Medical Progress? de Mark P. Khurana

The Trajectory of Discovery: What Determines the Rate and Direction of Medical Progress?

Autor Mark P. Khurana
en Limba Engleză Paperback – 12 apr 2023
Medical research works in trajectories. Scientists and researchers must choose to pursue certain scientific pathways and omit others, limited by resources, attention, and time. The trajectory of medical progress is therefore characterized by two crucial characteristics: rate and direction. These two components form the foundation for this book - what are the forces that determine the rate and direction of progress in medicine? This book brings together the worlds of scientific policy, economics, sociology, philosophy, and innovation to describe why the world of medical research looks the way it does. The book also addresses fundamental contemporary issues in medicine, how they influence progress, and how we might improve medical research going forward. The contemporary issues discussed include: flawed incentive structures, a concentration of power and resources among few actors and disease groups, the potential distortionary effects of lobbying by different scientific actors, and missing novelty in drug development.
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Specificații

ISBN-13: 9781009354431
ISBN-10: 1009354434
Pagini: 192
Dimensiuni: 156 x 234 x 9 mm
Greutate: 0.25 kg
Editura: Cambridge University Press
Colecția Cambridge University Press
Locul publicării:Cambridge, United Kingdom

Cuprins

Part I. Incentives, Context and Capital: 1. Citations as currency; 2. Hacking statistics; 3. The allure of prizes; 4. Streetlight effects; 5. Patented and regulated progress; 6. Teams and diversity; Part II. The Financial Determinants of Discovery: 7. The research marketplace; 8. Winners take all; 9. Public service; 10. The medici model; 11. The goldilocks zone; 12. Kindling creativity; Part III. Bending the Arc: 13. Lobbying for change; 14. Scientific elasticity; 15. Death of a star // new kids on the block; 16. Great emergencies; 17. Fraudulent findings; 18. Serendipity; 19. Converging paths; Part IV. Reflecting on the Trajectory: 20. Civic engagement; 21. Uncertainty; 22. Commercialization and power; 23. Morality and progress.

Recenzii

'With engaging examples and a surprising breadth of research, The Trajectory of Discovery, brilliantly illuminates how both the rate and trajectory of medical research rests on the incentives built into the scientific system and the social context in which research takes place. Khurana deftly applies a host of classical and new findings from across scientometrics, sociology of science, and the economics of innovation to the medical area and highlight why we (don't) know what we (don't) know. Through examples, theory, and empirical research, the book argues that discovery rests crucially on the aggregated choices of many scientists, whose actions are shaped by the social logic of scientific system - a logic that is not necessarily optimized for this endeavor. It will be a great read for social scientists interested in the intricacies of medical science, or doctors in search for explanations of why science works the way it does.' Emil Bargmann Madsen, Postdoctoral Researcher, Danish Centre for Studies in Research and Research Policy, Aarhus University
'The rate and direction of medical progress remain neglected topics for systematic study. Mark P. Khurana's The Trajectory of Discovery shines the spotlight on such issues and makes this what is likely to be the most important book on both biomedicine and science policy this year.' Tyler Cowen, Professor of Economics, George Mason University
'A compelling route into the contemporary world of science. With plenty of illuminating examples from biomedical research, Khurana gives us an insider's view into how prizes, important discoveries, easily-accessible tools, funding bubbles, temporary emergencies and crises have long-term effect on what scientists study, and contribute to determine whether science will ultimately progress or sluggish. It shows how patients' groups, philanthropic institutions, corporate lobbies and governments can have a say into what gets prioritized and discusses how some of the current obsessions of science, such as having positive findings, publishing first and cumulate citations pose additional frictions. The final portrait is a world where little room, if any, is left to academic freedom.' Chiara Franzoni, Professor of Applied Economics, School of Management, Polytechnic University of Milan

Notă biografică

Descriere

Explores the forces determining the trajectory of medical progress, bringing together scientific policy, economics, sociology and innovation.