Sienna Chambers is an unfortunate girl. Her father died in a road accident four years ago and her mother hasn't been able to recover from the tragedy. Sienna is almost sixteen and has to wrestle with a mother who is grief stricken and look after herself and work towards her ambition to be a doctor. She has set herself an difficult target, of achieving a medical degree from Cambridge University. It seems that fate is against her, trouble in school and trouble from the Children's Department and an assault charge hanging over her. It is a good thing she has friends especially Jennie, but Sienna sometimes feels it is her against the world.