The land degradation and water scarcity problems are global problems that face Jordan and have taken a large space in recent years, especially in agricultural land degradation. This may worsen in the coming years since the agricultural sector is considered one of the most important sources of gross domestic product at the state level--the only source of per capita income for people in some areas. Many natural factors, such as water and wind, and human factors, such as the wrong agricultural practices and lack of awareness of the agricultural as well as the misuse of groundwater resources, have contributed to the degradation of soil quality and deterioration of groundwater quality in Jordan. The types of degradation represented that affect lands and groundwater are (a) wrong farming practices through use and overuse of biocides and fertilizers and irrigation return flows as well as lack of agricultural management in agricultural soil protection and conservation methods, and (b) over-pumping of water that leads to salinization. Geoinformatics (Remote sensing, Geographical Information Systems, Global Positioning System) play an important role for evaluating, monitoring and investigating the environment and its components; it is used to determine land condition trends (whether conditions are getting worse, better, or staying the same), and is particularly beneficial for monitoring desertification and land changes over time. Therefore, geoinformatics techniques were used in investigating the impact of agricultural activities on land degradation in northeastern Jordan as a case study, through development of DRASTIC index (groundwater vulnerability) and assessment of the risk, as well as developing a model for the investigation of land degradation.