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Therapeutic Applications of Adenoviruses de Philip Ng

Therapeutic Applications of Adenoviruses: Gene and Cell Therapy

Editat de Philip Ng, Nicola Brunetti-Pierri
en Limba Engleză Paperback – 30 mar 2021
Adenoviruses are double stranded DNA viruses that have been used to study the process of DNA replication. Studies of the mode of action of adenovirally produced tumors in rodents led to the discovery of tumour supressor genes. The adenoviral vector is now the most used vector in clinical gene therapy especially for some kinds of cancers. The chapters in this book focus on the most up-to-date developments in the therapeutic applications of adenoviruses. The intended audience is individuals in the Life Sciences interested in therapeutic applications of adenoviruses. This book reviews the life history and immune responses to adenoviruses and summarizes various therapies implemented with the use of adenoviruses.
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Specificații

ISBN-13: 9780367658182
ISBN-10: 0367658186
Pagini: 256
Dimensiuni: 156 x 234 mm
Greutate: 0.45 kg
Ediția:1
Editura: CRC Press
Colecția CRC Press
Seria Gene and Cell Therapy

Cuprins

Adenovirus Biology: Virus structure and life cycle. Immune responses to adenovirus. Helper-dependent adenoviral vectors for gene and cell therapy. Genetic and capsid modified Adenovirus. Adenovirus for vaccination. FGAd and HDAd. Adenovirus vectors for cancer therapy. Adenovirus-based hybrid vectors. FDA expectations and requirements of adenoviral products.

Notă biografică

Philip Ng is jointly an Associate Professor of Department of Molecular and Human Genetics and the Program in Translational Biology & Molecular Medicine at the Baylor College of Medicine. He is interested in developing gene therapies for genetic diseases using helper-dependent adenoviral vectors (HDAd).


Nicola Brunett-Pieri is an Associate Professor in the Department of Translational Medicine at Federico II University in Naples and an Associate Investigator at Telethon Institute of Genetics and Medicine (TIGEM).

Descriere

This book will review the life history and immune responses to adenoviruses as well summarize various therapies implemented with the use of adenoviruses.