Therapeutic Discovery in Psychiatry
Editat de Mark Tricklebanken Limba Engleză Hardback – 31 ian 2025
- Provides a comprehensive guide to developing new drugs for psychiatric disorders
- Discusses technologies and techniques for choosing drug targets
- Presents criteria for what makes a compound worth testing
- Addresses medicinal chemistry, pharmacokinetics, and biomarkers of drug action
- Contains clinical trial design including reproducibility and safety pharmacology
- Reviews next steps including patents, venture capital, business development, and licensing
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Specificații
ISBN-13: 9780128210413
ISBN-10: 0128210419
Pagini: 600
Dimensiuni: 216 x 276 mm
Editura: ELSEVIER SCIENCE
ISBN-10: 0128210419
Pagini: 600
Dimensiuni: 216 x 276 mm
Editura: ELSEVIER SCIENCE
Cuprins
1. Pharmacology basics
2. Neuroscience basics
3. Immunology basics
4. History of Psychopharmacology
5. Getting past serendipity
6. Drug Profiling in vitro
7. Drug Profiling in vivo
8. Brain imaging
9. Neurobiology Imaging and genetics of Psychiatric Disorders
10. Developmental disorders
11. Choosing drug targets:
12. Ethics of animal use
13. Biomarkers of drug action
14. Monitoring regional neuronal activation, fMRI, oxygen amperometry, optogenetics
15. Medicinal Chemistry
16. Design of experimental medicine studies for Clinical Proof of Concept
17. Drug formulation and Pharmacokinetics, including nanoscience The Blood Brain Barrier
18. Safety Pharmacology
19. Clinical trial design
20. Drug targets that failed clinically: what went wrong?
21. Genomics in drug discovery and target validation
22. Clinical translation
23. Business Development and licensing
24. Patent law
25. Entrepreneurial development and venture capitol
26. Pharmacovigilence and regulatory agencies, FDA and EMA
27. Examples of success and innovation
2. Neuroscience basics
3. Immunology basics
4. History of Psychopharmacology
5. Getting past serendipity
6. Drug Profiling in vitro
7. Drug Profiling in vivo
8. Brain imaging
9. Neurobiology Imaging and genetics of Psychiatric Disorders
10. Developmental disorders
11. Choosing drug targets:
12. Ethics of animal use
13. Biomarkers of drug action
14. Monitoring regional neuronal activation, fMRI, oxygen amperometry, optogenetics
15. Medicinal Chemistry
16. Design of experimental medicine studies for Clinical Proof of Concept
17. Drug formulation and Pharmacokinetics, including nanoscience The Blood Brain Barrier
18. Safety Pharmacology
19. Clinical trial design
20. Drug targets that failed clinically: what went wrong?
21. Genomics in drug discovery and target validation
22. Clinical translation
23. Business Development and licensing
24. Patent law
25. Entrepreneurial development and venture capitol
26. Pharmacovigilence and regulatory agencies, FDA and EMA
27. Examples of success and innovation