Restoration repair of tooth structures, do not stop caries, have a finite life span and are susceptible to disease. Therefore a shift has been identified from management of dental caries towards improved diagnosis of non-cavitated, incipient lesion and treatment for prevention and arrest of such lesion. One of the most powerful tool or weapon that has been proved beyond doubt, to control and prevent dental caries in past 50 years is Fluoride. Various modalities i.e. water fluoridation; fluoride dentifrices, mouth rinses, varnishes and gel etc have played a significant role in decline of dental caries in western world and other developed countries. This work examined the caries-inhibiting effect of a topically applied APF gel. This book is very useful for students in general and dental and public health professional in particular to seek and provide preventive care for children.