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Towards Efficient Designing of Safe Nanomaterials: Innovative Merge of Computational Approaches and Experimental Techniques: RSC Nanoscience & Nanotechnology, cartea 25

Editat de Jerzy Leszczynski, Tomasz Puzyn, Harry Kroto
en Limba Engleză Hardback – 26 sep 2012
The expanding field of nanotechnology is now one of the most promising areas of science. However, because some nanoparticles can have a negative impact on human health and the environment, the design of novel materials must always be accompanied by a comprehensive risk assessment. Until now, the information on the methods available has been fragmented and incomplete. This book is the first to provide a comprehensive review of recent progress and challenges in the risk assessment of nanomaterials by empirical and computational techniques. Topics covered include: benefits versus risks, carbon based nanomaterials, environmental detection and quantitative analysis, chemometric modelling, human exposure assessment, toxicity testing, nano-QSAR, risk assessment strategies, policy and regulatory frameworks.
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Specificații

ISBN-13: 9781849734530
ISBN-10: 1849734534
Pagini: 378
Dimensiuni: 162 x 237 x 27 mm
Greutate: 0.74 kg
Editura: Royal Society Of Chemistry
Seria RSC Nanoscience & Nanotechnology


Cuprins

Nanomaterials: benefits and risks; Experimental characterizing structural properties of nanoparticles related to their toxicity; Structure-property mapping methods; Modelling properties of nanoparticles based on quantum-mechanical methods; Ontology; Empirical determination of nanoparticles' behavior in environmental media; Computational mass-ballance modeling of environmental transport and fate of engineered nanoparticles; Pharmacokinetics and biological fate of nanoparticles; Pharmacokinetic-based modeling; Modeling kinetics of nanoparticle cellular interaction and transport; Toxicity and Ecotoxicity testing of engineered nanoparticles - experimental point of view; In vitro toxicity of nanomaterials; In vivo testing; Computational modeling of interactions between nanoparticles and other species; Comprehensive Environmental Assessment as a Tool for Nanomaterial Risk Assessment; Predicting oxidative stress; Nano-QSAR

Notă biografică

Jerzy Leszczynski is Professor of Chemistry and a President's Distinguished Fellow. Director of Interdisciplinary Nanotoxicity Center. Author and co-author of almost 700 peer-reviewed papers (H index 47) and 50 book chapters.

Textul de pe ultima copertă

Nanotechnology is one of the most promising and rapidly-expanding areas of science and the development of new materials on the nanoscale can benefit many disciplines, including chemistry, physics, and medicine. However, novel nanomaterials can possess a negative impact on human health and the environment and their development should be accompanied by a comprehensive risk assessment. Until now, information on the methods available for this purpose has been fragmented. This book presents a comprehensive review of the latest achievements in risk-assessing novel nanomaterials, drawing on expertise from across the globe. Both empirical methodologies and computational techniques are presented, and the editors advise that both groups of techniques are required for a complete risk assessment. Anyone developing new nanomaterials (in academia or industry) will find this book an essential reference. Toxicologists and environmental scientists will also benefit from learning the latest tools used for detecting nanomaterials in the environment.