Transcriptomics in Atherosclerosis: Deciphering Molecular Signatures and Advancing Therapeutic Strategies
Editat de Yvan Devaux, Miron Sopicen Limba Engleză Paperback – sep 2025
- Unravels the molecular intricacies of atherosclerosis using the latest transcriptomic technologies, offering new perspectives on disease mechanisms and potential therapeutic targets
- Highlights the transformative potential of RNA molecules in advancing diagnostics and developing novel RNA-based treatments for personalized medicine in cardiovascular care
- Provides actionable insights into translating transcriptomic findings into clinical applications, enhancing patient stratification, and treatment strategies
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Specificații
ISBN-13: 9780443330643
ISBN-10: 0443330646
Pagini: 300
Dimensiuni: 191 x 235 mm
Editura: ELSEVIER SCIENCE
ISBN-10: 0443330646
Pagini: 300
Dimensiuni: 191 x 235 mm
Editura: ELSEVIER SCIENCE
Cuprins
Section I – Introduction
1. Atherosclerotic CVD – epidemiology and current challenges in management
2. Atherosclerotic Plaque Phenotypes: Unraveling Complexity and Heterogeneity
Section II – The role of RNAs in atherosclerosis progression and development
3. Biogenesis and mechanisms of action of ncRNAs
4. The role of ncRNA in plaque development and progression
5. Signaling Pathways Regulating Gene Expression in Atherosclerosis
6. Epitranscriptomics and Atherosclerosis:
Section III – Transcriptomic Profiling of Atherosclerotic Lesions
7. Essentials of Transcriptomic Methods: Navigating Through RNA Sequencing and Beyond
8. Bridging the Gap in Transcriptomics: From Animal to Human Studies in Atherosclerosis
9. Translating Transcriptomics into Clinical Practice: Utilizing Gene Expression Patterns for Advanced Patient Phenotyping and Stratification in Atherosclerosis Optimizing Study Design for In-depth Transcriptomic Analysis of Atherosclerotic Plaques
10. Unveiling Sex-Specific Transcriptomic Mechanisms in Atherosclerosis
Section IV – Integrating Multi-Omics Approaches in Atherosclerosis Research
11. Combining Transcriptomics with Genomics, Proteomics, and Metabolomics
12. Insights into Gene Regulatory Networks in Vascular Pathology
13. Systems Biology and Network Analysis
14. Use of artificial intelligence and machine learning for multi-omics
Section V – RNA-Based Theranostics: Revolutionizing Treatment and Diagnosis in Atherosclerotic Cardiovascular Disease
15. RNA Therapeutics in Atherosclerosis:
16. RNA Therapeutic Delivery Systems – advances and challenges
17. Exploring Circulating RNAs: Emerging Biomarkers for Atherosclerosis Detection and Monitoring
Section VI – Conclusion
18. Future Directions and Emerging Technologies in Transcriptomic Research and Atherosclerosis
1. Atherosclerotic CVD – epidemiology and current challenges in management
2. Atherosclerotic Plaque Phenotypes: Unraveling Complexity and Heterogeneity
Section II – The role of RNAs in atherosclerosis progression and development
3. Biogenesis and mechanisms of action of ncRNAs
4. The role of ncRNA in plaque development and progression
5. Signaling Pathways Regulating Gene Expression in Atherosclerosis
6. Epitranscriptomics and Atherosclerosis:
Section III – Transcriptomic Profiling of Atherosclerotic Lesions
7. Essentials of Transcriptomic Methods: Navigating Through RNA Sequencing and Beyond
8. Bridging the Gap in Transcriptomics: From Animal to Human Studies in Atherosclerosis
9. Translating Transcriptomics into Clinical Practice: Utilizing Gene Expression Patterns for Advanced Patient Phenotyping and Stratification in Atherosclerosis Optimizing Study Design for In-depth Transcriptomic Analysis of Atherosclerotic Plaques
10. Unveiling Sex-Specific Transcriptomic Mechanisms in Atherosclerosis
Section IV – Integrating Multi-Omics Approaches in Atherosclerosis Research
11. Combining Transcriptomics with Genomics, Proteomics, and Metabolomics
12. Insights into Gene Regulatory Networks in Vascular Pathology
13. Systems Biology and Network Analysis
14. Use of artificial intelligence and machine learning for multi-omics
Section V – RNA-Based Theranostics: Revolutionizing Treatment and Diagnosis in Atherosclerotic Cardiovascular Disease
15. RNA Therapeutics in Atherosclerosis:
16. RNA Therapeutic Delivery Systems – advances and challenges
17. Exploring Circulating RNAs: Emerging Biomarkers for Atherosclerosis Detection and Monitoring
Section VI – Conclusion
18. Future Directions and Emerging Technologies in Transcriptomic Research and Atherosclerosis