Transforming Proteins of DNA Tumor Viruses: Current Topics in Microbiology and Immunology, cartea 144
Editat de Rolf Knippers, Arnold J. Levineen Limba Engleză Paperback – 16 dec 2011
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Specificații
ISBN-13: 9783642745805
ISBN-10: 3642745806
Pagini: 304
Ilustrații: XIV, 284 p.
Dimensiuni: 170 x 242 x 16 mm
Greutate: 0.49 kg
Ediția:Softcover reprint of the original 1st ed. 1989
Editura: Springer Berlin, Heidelberg
Colecția Springer
Seria Current Topics in Microbiology and Immunology
Locul publicării:Berlin, Heidelberg, Germany
ISBN-10: 3642745806
Pagini: 304
Ilustrații: XIV, 284 p.
Dimensiuni: 170 x 242 x 16 mm
Greutate: 0.49 kg
Ediția:Softcover reprint of the original 1st ed. 1989
Editura: Springer Berlin, Heidelberg
Colecția Springer
Seria Current Topics in Microbiology and Immunology
Locul publicării:Berlin, Heidelberg, Germany
Public țintă
ResearchCuprins
I: The Transforming Protein of Simian Virus 40: Large T antigen and Its Interactions with the Cellular Protein p53.- Structure and Function of SV40 Large T Antigen: Communication Between Functional Domains.- A Genetic Analysis of the Zinc Finger of SV40 Large T Antigen.- Effects of Amino Acid Phosphorylation on the DNA Binding Properties of Large T Antigen.- SV40 T Antigen Catalyzed Duplex DNA Unwinding.- Control of Transcription In Vitro from Simian Virus 40 Promoters by Proteins from Viral Minichromosomes.- Dissection of the T Antigen/mouse p53 Complex and Its Inhibitory Effects on Viral Origin-Directed DNA Replication In Vivo and In Vitro.- Interactions Between SV40 and Cellular Oncogenes in the Transformation of Primary Rat Cells.- Metabolic Stabilization of p53 in SV40 Transformed Cells Correlates with Expression of the Transformed Phenotype but is Independent from Complex Formation with SV40 Large T Antigen.- SV40 Large T Antigen Induces a Protein Kinase Responsible for Phosphorylation of the Cellular Protein p53.- Evidence for Threshold Effects in Transformation of Pancreatic ß-Cells by SV40 T Antigen in Transgenic Mice.- The Biological Activity of Early SV40 Antisense RNA and DNA Molecules.- II: Polyomavirus Middle T Antigen.- Mechanism of Activation of Complexed pp60src by the Middle T Antigen of Polyomavirus.- Further characterisation of the Complex Containing Middle T Antigen and pp60src.- The Mutagenic and Immortalizing Potential of Polyomavirus Large T Antigen.- III: Transforming Functions of Papillomaviruses.- Structure, Activity, and Regulation of the Bovine Papillomavirus E5 Gene and Its Transforming Protein Product.- Functional and Sequence Similarities Between HPV-16 E7 and Adenovirus E1A.- Two Independently Transforming Functions of HumanPapillomavirus 8.- Human Papillomavirus Early Gene Products and Maintenance of Cervical Cancer Cells In Vitro.- IV: Transformation by Adenoviruses.- Adenovirus Terminal Protein Mediates Efficient and Timely Activation of Viral Transcription.- Transcriptional Activation of Adenoviral Early Genes.- Suppression of Cellular Gene Activity in Adenovirus-Transformed Cells.- Recombination Between Adenovirus DNA and the Mammalian Genome.- V: Herpesviruses: The Cellular and Molecular Biology of Epstein-Barr Virus.- Epstein-Barr Virus DNA Replication.- Characterization of the BNLF-1 Oncogene of Epstein-Barr Virus.- Genes for Synthesis of Deoxythymidylate Monophosphate in T-Cell Lymphoma-Inducing Herpesviruses of Nonhuman Primates.- VI: Hepatitis B Virus and Liver Cancer.- Analysis of Hepatitis-B Virus Gene Functions in Tissue Culture and In Vivo.- Transactivation by Hepatitis B Virus may Contribute to Hepatocarcinogenesis.