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Translating Biomaterials for Bone Graft: Bench-top to Clinical Applications

Editat de Joo L. Ong, Teja Guda
en Limba Engleză Paperback – 30 mar 2021
Translating Biomaterials for Bone Graft: Bench-top to Clinical Applications brings together the current translational research in bone tissue engineering, from design to application – from materials, drugs and biologic delivery used for bone graft applications to pre-clinical and clinical considerations. The book also discusses the regulatory approval pathways, which involves consideration of the class of devices; whether they are similar to existing solutions, minimal manipulation of donor tissue or completely novel materials, drugs and biologics. These considerations drive the ability to successfully transition the latest generations of bone graft materials into the clinics. Chapters come from materials scientists, clinicians, researchers, and consultants and provide a holistic understanding of the field. As such, the book is a state-of-the-art reference to bone therapies and should appeal to clinicians, scientists, as well as students interested in the current research and/or practices in the field of bone regeneration and restoration.
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Specificații

ISBN-13: 9780367658243
ISBN-10: 0367658240
Pagini: 275
Dimensiuni: 156 x 234 x 15 mm
Greutate: 0.4 kg
Ediția:1
Editura: CRC Press
Colecția CRC Press

Public țintă

Postgraduate and Professional Reference

Cuprins

Editorial Foreword. Introduction. Bone Grafting Evolution. Materials. Ceramics. Polymers. Composites. Currently available grafts on the market. Growth Factors. BMP-2 and BMP-7. Other growth factors and delivery mechanisms. DBM and grafts. Cells and Biologics. Cell sources for orthopaedic defects. Cell sources for craniofacial defects. Animal Models for regeneration. Infection and antibiotics. Clinical Perspective. Orthopaedic Trauma. Spinal reconstruction. Dental and craniofacial reconstruction. Regulatory and ease-of-use

Descriere

The book presents current translational research of bone tissue engineering, from bench-top to clinical applications. It discusses all stages of the therapy development pipeline ranging from materials properties to pre-clinical studies and clinical uses. The chapters are written by basic materials scientists, clinicians, and researchers. This bo