Translational Immunology: Mechanisms and Pharmacologic Approaches
Autor Seng-Lai Tanen Limba Engleză Hardback – 7 dec 2015
Readers will gain an understanding of the rationale and mechanisms underlying current and emerging pharmacologic approaches for interventional immunology, the gaps therein, and new ideas for better and safer therapeutic approaches, and physicians will glean information about pharmacological limitations in altering disease progression and complications. This reference on the translational realization of the burgeoning findings in immunology provides a go-to reference for experienced professional clinicians, researchers, industry scientists, and those seeking more information on the field.
- Delivers comprehensive coverage of seminal human immunology discoveries and the resulting impact on therapeutic strategies
- Presents potential novel targets and approaches for clinical applications in organ specific and systemic autoimmunity, transplant rejection, cancer, and vaccine development
- Discusses lessons learned from successful and failed clinical trials with specific interventions, including pharmacological issues and limitations, and complications due to immunosuppression
- Provides information on new strategies and outstanding issues that should be addressed in future research
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Specificații
ISBN-13: 9780128015773
ISBN-10: 0128015772
Pagini: 384
Dimensiuni: 191 x 235 x 23 mm
Greutate: 1.02 kg
Editura: ELSEVIER SCIENCE
ISBN-10: 0128015772
Pagini: 384
Dimensiuni: 191 x 235 x 23 mm
Greutate: 1.02 kg
Editura: ELSEVIER SCIENCE
Cuprins
Preface Section A: Human Immunology1. Systems Immunology2. Primary Immunodeficiencies3. Phenome-wide association study (PheWAS)4. Gene Regulatory Network5. TCR Repertoire Analysis Section B: Current and Emerging Pharmacological Targets6. TH177. TH98. TFH9. Regulatory T cells10. Regulatory B cells Section C: New Approaches11. Immune Tolerance Induction12. Humanized Mouse Models 13. Patient Stratification and Biomarkers