Dermatopharmacy and -pharmacology have developed enormously over the past years, especially thanks to the rapid technical development of analytical, synthesis and diagnostic procedures. In addition, genetechnical and molecular-biological methods have brought innovation not only in systemic, but especially also in topical applications of medicinal and active substances. Modern vehicle systems have initiated a new age in galenics and make it possible to apply even high-molecular or hard-todissolve substances in therapeutic doses.With detailed knowledge of the structure and function of the skin, as well as the regulation of metabolic processes, there is an increasing merging of biological processes with pharmacological-therapeutic manipulations.Despite these positive developments, dermatopharmacy needs enthusiastic, engaged persons with a broad range of ideas, who will work out the basic scientific foundation, design the practical relationships and lead in the conception of an effective, marketable product.