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Understanding Parkinson's Disease: A Personal and Professional View

Autor Richard B. Rosenbaum M.D.
en Limba Engleză Hardback – 29 oct 2006 – vârsta până la 17 ani
A neurologist whose father suffers from Parkinson's provides a layreader-friendly explanation of the disease, its history, development, treatment and modern advances that may ultimately lead to a cure. Rosenbaum's professional view is as a clinical neurologist who regularly cares for patients with the progressive neurological deterioration caused by Parkinson's Disease. His personal experience with his father, a retired surgeon, further powers his quest to give patients, family members and caregivers what they need to know. Topics covered include challenges of correct diagnosis, variations in prognosis, investigations of causes including exciting progress in possible toxins and genetic factors that play a role, and different treatment options including natural remedies as well as new drugs for symptom treatment. Rosenbaum also explains research efforts to find a preventative drug, modern surgical options and hopes for stem cell or gene therapy.In this work, Rosenbaum blends historical and medical research with illustrations from the patients in his professional life, and from his dad on the homefront, to give us a clear and comprehensive understanding of Parkinson's. He also includes writing from and attention to well-known individuals affected by this disorder-among them actor Michael J. Fox.
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Specificații

ISBN-13: 9780275991661
ISBN-10: 0275991660
Pagini: 264
Dimensiuni: 156 x 235 x 25 mm
Greutate: 0.55 kg
Editura: Bloomsbury Publishing
Colecția Praeger
Locul publicării:New York, United States

Notă biografică

Richard B. Rosenbaum, M.D. is a Clinical Professor of Neurology at Oregon Health Sciences University, and a practicing Neurologist at The Oregon Clinic. He is a board-certified Neurologist, a Diplomate of the American Board of Internal Medicine and also the American Board of Electrodiagnostic Medicine. He earned his medical degree at Harvard University Medical School.

Cuprins

Acknowledgments Introduction 1. THE DIAGNOSTIC CONVERSATION-DIAGNOSIS AND PROGNOSIS OF PARKINSON'S DISEASE Making the Diagnosis James Parkinson and the Shaking Palsy Jean Charcot and Better Examinations Checking Diagnostic Accuracy Specificity and Sensitivity Prognosis The Hoehn and Yahr Scale The Unified Parkinson's Disease Rating Scale 2. PATHOLOGY OF PARKINSON'S DISEASE What Part of the Brain Fails in Parkinson's Disease? Nerve Cell Connections Chemical Pathology of Parkinson's Disease 3. IS THERE AN EPIDEMIC OF PARKINSON'S DISEASE? Epidemiology of Parkinson's Disease John Snow-The Father of Epidemiology Koch's Postulates Investigating Clusters of Parkinson's Disease Kuru and Creutzfeldt-Jakob Disease Does Smoking Cause Parkinson's Disease? Causation versus Association-The Hill Criteria Epidemiology of Smoking and Parkinson's Disease Pesticides, Head Trauma, and Parkinson's Disease Parkinson's at the Manor 4. CAUSES OF PARKINSON'S DISEASE Does an Infection Cause Parkinson's Disease? When Prophecy Fails Do Toxins Cause Parkinson's Disease? An Answer from the Frozen Addicts Do Genes Cause Parkinson's Disease? All Disease Is Genetic Disease 5. MEDICATIONS FOR PARKINSON'S DISEASE The Herbal Tradition Herbal Treatment of Parkinson's Disease Awakenings-L-Dopa Therapy Dopamine and Schizophrenia-The Dopamine Receptor Rational Drug Therapy-Trying to Prevent Progression of Parkinson's Disease Coenzyme Q10-Another Quest for Neuroprotection The Challenges of Taking L-Dopa 6. IMAGES OF THE BRAIN-A PICTURE OF THE BRAIN IS WORTH A THOUSAND WORDS Imaging and Diagnosis Imaging and Presymptomatic Diagnosis Imaging and Disease Progression 7. A BETTER MODEL OF PARKINSON'S DISEASE Dopamine Nerve Cells Connect to Many Parts of the Brain Dopamine is One of Many Neurotransmitters That Are Important in Parkinson's Disease Patients with Parkinson's Disease Lose Cells from Many Areas of the Brain 8. BRAIN SURGERY FOR PARKINSON'S DISEASE Can Destroying Part of the Brain Be Good? "Brain Transplantation"-Implanting New Brain Cells Gene Therapy 9. LIVING WITH PARKINSON'S DISEASE Mood, Behavior, and Parkinson's Disease Can L-Dopa Make People Gamble? Are Parkinson's Disease and Alzheimer's Disease Related? Sleep and Parkinson's Disease Fall and Injury Prevention 10. CONCLUSIONS What Happens to Brain Cells to Cause Parkinson's Disease? Living Better with Parkinson's Disease The Story of Parkinson's Disease Is Not Finished Appendix: Reading about Parkinson's Disease Glossary Notes Index

Recenzii

Rosenbaum melds his professional experiences as a clinical neurologist and professor of neurology with personal experiences to provide an insightful overview of Parkinson's disease. He is remarkably successful in his ambitious attempt to cover the history, etiology, pathology, clinical manifestations, treatment options, and nonpharmacologic management of this neurological disorder for a wide readership. The author provides concise, easily digestible introductions to basic medically related scientific concepts such as incidence/prevalence of disease, genetic inheritance, and test sensitivity/specificity as necessary for comprehension of the substantive discussions in each chapter. Engaging descriptions of medical discoveries, drug development, medical practice issues, and patient-physician communication are wide-ranging and logically organized..[t]he method of synthesizing information pertaining to Parkinson's disease is applicable to any disease entity, as are the many pearls regarding patient care. This book will be useful for those afflicted with Parkinson's disease and for families, caregivers, students seeking a career in any of the health professions, and others interested in an understandable illustration of how to thoughtfully explore a disease and its treatment. Recommended. All levels.
Writing for those afflicted with Parkinson's disease and their families, Rosenbaum hopes to aid his readers' decision-making by providing a level of understanding of the disease, its course, causes, and treatments equivalent to a student who has taken a one-semester course on the illness..[h]e has attempted to keep jargon and complex details to a relative minimum.