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Understanding the Pandemic: Pathophysiology, Transmission, and Treatment of COVID-19 de Shampa Chatterjee

Understanding the Pandemic: Pathophysiology, Transmission, and Treatment of COVID-19

Editat de Shampa Chatterjee, Amaro Nunes Duarte Neto, Marco Cascella, Sonia Villapol, Anand Viswanathan, Aravind Ganesh, Ching Lung Lai, Giuseppe Remuzzi
en Limba Engleză Paperback – 8 noi 2024
Understanding the Pandemic: Pathophysiology, Transmission, and Treatment of COVID-19 aims to cover all aspects of COVID-19 infection from the virus, transmission, pathogenesis, immune-inflammation response, systemic injury, organ damage, associated factors, and comorbidities that drive mortality. Organized into ten sections, the book aims to provide a comprehensive examination of the impact of COVID-19. The book begins a review of coronaviruses, their structure and mechanism of action. The book goes on to discuss the immune response to the virus and its effect on various organs. It examines clinical cases based on an observations and postmortem studies. Other topics include the long-term effects of COVD-19, vaccines, and public health response.


  • Discusses coronavirus and their similarities and differences in origin and transmission as well as a review of their structure and mechanisms of action
  • Examines the immune-inflammation responses to COVID-19 and the organ-specific impact of the disease
  • Covers vaccines and other treatment protocols and public health responses in various geographic locations
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Specificații

ISBN-13: 9780443191701
ISBN-10: 0443191700
Pagini: 950
Dimensiuni: 191 x 235 x 47 mm
Greutate: 1.93 kg
Editura: ELSEVIER SCIENCE

Cuprins

Section 1: Coronaviruses (including SARS 1 and MERS), the Structure (sequence), Mechanism of Action Introduction 1. Origin, Evolution and Spread of SARS-CoV-2 2. SARS-CoV-2 Spike Proteins in Infectivity 3. Structural and functional properties of the SARS-CoV-2 spike protein: potential vaccine and drug development for COVID-19 4. Population-Specific Polymorphisms and SARS-CoV-2 Infectivity 5. Insights into SARS-CoV-2 Structure: Approaches and Action of SARS-CoV-2 Main Protease Inhibitors 6. SARS-CoV-2, SARS-CoV, and MERS-COV: Similarities and Differences in Origin and Transmission Section 2: Inflammation and Immune Response to SARS-CoV-2 Introduction 7. Characterization of the Immune Response with Viral Attack 8. Inflammation, Cytokines and COVID-19 Severity 9. Immunological Considerations for COVID-19: Vaccines and Other Protective Strategies 10. Virus-specific T cell response in SARS-CoV-2 infection and vaccinations 11. Oral and Gut Inflammation and Microbiota with COVID-19 12. Implications of Inflammation: Bone and Joint Health with COVID-19 13. COVID-19 and immune dysfunction: Consequences, and natural remedies for management Section 3: Pathological Findings with Clinical Correlation Introduction 14. Pulmonary Pathology of Severe Covid-19 15. Histopathological Analysis of the Cardiovascular System in severe COVID-19 16. Postmortem Neuropathology in COVID-19 17. Renal Pathology in Severe Covid-19 Section 4: The Blood Vessels and COVID-19: Vascular Dysfunction and Coagulopathies Introduction 18. Vascular Manifestations of COVID-19: Endothelial Dysfunction and Damage 19. Immunothrombosis involvement in COVID-19 20. COVID-19 associated coagulopathy 21. D-dimer in systemic circulation and COVID-19 outcome 22. Hypercoagulability in COVID-19 Section 5: Neuro-COVID-19 and its Long-Term Implications Introduction 23. COVID and the Nervous System: Mechanisms and Consequences 24. Neuroinflammation: Unraveling Acute and Long COVID-19 Effects 25. Acute and Post-acute Neurologic and Psychiatric Manifestations in COVID-19 26. Pediatric Neurological and Neuropsychiatric Manifestations of COVID-19 27. Understanding the Pandemic: Pathophysiology, Transmission, and Treatment of Covid-19 Section 6: Should Covid-19 Concern Nephrologists? Why and to What Extent?" Introduction 28. Acute Kidney Injury with COvid-19: Mechanisms, Management, and Long-term Outcomes 29. Models and Cellular Monolayers to Study the Effect of SARS-CoV-2 on Kidneys 30. Clinical implications of COVID-19 in chronic kidney disease and end-stage kidney disease Section 7: Long COVID-19 (long term effects - summarizing of clinical reports in literature) Introduction 31. Long COVID or Post-Acute Sequalae of COVID: An introduction 32. Long COVID: Pathophysiology and classification 33. Gender differences in Sequelae from COVID-19 Infection 34. Characterizing Long COVID-19: Lessons in the Clinic. 35. Implications of Long COVID for the Global Health Care System Section 8: The Vaccines Introduction 36. COVID-19: The Vaccine Development Strategies 37. mRNA vaccines: The New Frontier 38. Covid-19 vaccines: A Comprehensive review of Safety and Efficacy Section 9: Handling the Spread: Public Health and Social Measures Introduction 39. Lockdown measures during the COVID-19 pandemic 40. Efficacy of Facial masks against COVID-19 41. Vaccination Policies 42. Navigating the Impact of COVID-19 School Closures on Child Health, Education, and Society: A Call to Embrace Civil Discourse Across Identities, Sectors, and Disciplines 43. The Effect of the Pandemic on Care for Other Health Conditions 44. The role of smartphone-assisted tools for Covid-19 diagnostic, treatment, and quarantine Section 10: From the Editors’ desk 45. What have we learnt from the COVID-19 pandemic?