As worldwide urbanization increases and our adversaries seek to use the urban terrain to asymmetrically engage US forces, the US military must be able to effectively conduct military operations in the urban environment that maximize maneuverability, flexibility, and lethality, while minimizing the risk to our forces. Not only must our warfighters have timely, reliable information about the urban terrain, they must also possess the capability to effectively address these threats to seize the initiative from our adversary, allowing us to dictate where and when to accept the fight. This book suggests that unmanned aerial vehicles (UAVs) is one system, although accepted for its value in providing our warfighters with enhanced information, surveillance, and reconnaissance (ISR) capabilities, has more to offer. In the fluid urban environment, ISR is only one critical aspect to successful mission accomplishment; UAVs can be used to conduct other key missions, as well. It is proposed they could be used to overcome communications shortfalls; look inside buildings to ascertain occupancy and purpose; detect, identify, track, and target enemy threats; and sense out mines and weapons of mass destruction employment. The conclusion is UAVs have demonstrated their potential usefulness. However, the US military needs to continue to investigate other missions against which to employ UAVs to take advantage of their inherent flexibility and maneuverability to enhance our urban warfighting capabilities. Further, UAVs are not viewed as the panacea for the challenging problems encountered in urban operations, they should be employed to complement manned aircraft. However, we need to address the unmanned manned force mix and doctrinal issues to maximize their utility.