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Using CNS Autopsy Tissue in Psychiatric Research: A Practical Guide

Autor Brian Dean, Thomas M Hyde, Joel E Kleinman
en Limba Engleză Hardback – 25 mar 1999
Essential for the laboratory, this practical manual presents a wide variety of techniques associated with the use of human CNS tissue obtained at autopsy. The book contains detailed methodologies in discrete chapters written by an expert in the specific field. It also addresses the potential for extending molecular studies in brain tissue obtain
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Specificații

ISBN-13: 9789057022982
ISBN-10: 9057022982
Pagini: 200
Dimensiuni: 156 x 234 x 17 mm
Greutate: 0.6 kg
Ediția:1
Editura: Taylor & Francis
Colecția CRC Press
Locul publicării:Oxford, United Kingdom

Cuprins

Foreword 1 The Collection of Tissue at Autopsy: Practical and Ethical Issues 2 Psychiatric Diagnosis After Death: The Problems of Accurate Diagnosis from Case History Review and Relative Interviews 3 Membrane Binding Assays: Membrane Preparation and Assay Development 4 The Localisation and Quantification of Molecular Changes in the Human Brain Using In Situ Radioligand Binding and Autoradiography 5 In Situ Hybridisation Histochemistry: Application to Human Brain Tissue 6 Immunohistochemistry Techniques Applicable for Use with Human Brain Tissue 7 The Processing and Use of Postmortem Human Brain Tissue for Electron Microscopy 8 Isolating Components of Human Brain: The Purification of A? and the Alzheimer’s Amyloid Precursor Protein 9 Analysis of Receptor Systems in Schizophrenia Using Tissue Obtained at Autopsy and Neuroimaging

Notă biografică

Brian Dean, Mental Health Research Institute of Victoria, Parkville, Australia. Thomas M Hyde, Joel E Kleinman, both National Institute of Mental Health, Washington DC, USA.

Descriere

Essential for the laboratory, this practical manual presents a wide variety of techniques associated with the use of human CNS tissue obtained at autopsy. The book contains detailed methodologies in discrete chapters written by an expert in the specific field.