In this issue of Medical Clinics of North America, guest editors Drs. Geno Merli and Raghu Kolluri bring their considerable expertise to the topic of Vascular Medicine. Top experts in the field provide evidence-based recommendations on vascular issues and diseases for those in primary care, non-vascular medicine specialists, and nurse practitioners, including articles on atherosclerotic disease, peripheral artery disease, lower extremity vascular ulcers, vasculitis, vascular imaging for the primary care provider, and more.