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Vertebrate Eye Development: Results and Problems in Cell Differentiation, cartea 31

Editat de M. Elizabeth Fini
en Limba Engleză Paperback – 31 aug 2012
"Who would believe that so small a space could contain the images of all the universe?" Leonardo da Vinci The last years of the 20th century have found the discipline of Developmental Biology returning to its original position at the forefront of biological re­ search. This progress can be attributed to the burgeoning knowledge base on molecules and gene families, and to the power of the molecular genetic ap­ proach. Topping the list of organ systems which have provided the most significant advances would have to be the eye. The vertebrate eye was one of the classic embryologic models, used to demonstrate many important prin­ ciples, including the concepts of inductive tissue interactions first put forth in the early 1900s. Within the last decade of this century, a return to some of the old questions with the new approaches has put eye development back into the limelight. I find this a highly appropriate topic for a book which aims to spark research for the new millennium. We begin with a chapter that discusses the anatomy of eye development, providing the basic reference information for the chapters that follow. A novel aspect of this introduction is the connection made between develop­ mental strategies and the eye's optical function. What also emerges from this chapter is the number of important eye structures that have barely been touched by the modern developmental biologist. Work on cornea and ante­ rior chamber development has lagged behind lens and retina.
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Specificații

ISBN-13: 9783642536786
ISBN-10: 3642536786
Pagini: 304
Ilustrații: XIV, 288 p. 74 illus., 2 illus. in color.
Dimensiuni: 155 x 235 x 20 mm
Greutate: 0.43 kg
Ediția:Softcover reprint of the original 1st ed. 2000
Editura: Springer Berlin, Heidelberg
Colecția Springer
Seria Results and Problems in Cell Differentiation

Locul publicării:Berlin, Heidelberg, Germany

Public țintă

Research

Cuprins

Overview.- Vertebrate Eye Development and Refractive Function: An Overview.- Early Pattern Formation.- Pax6 and the Genetic Control of Early Eye Development.- Early Retinal Development in Drosophila.- Embryonic Induction.- Induction of the Lens.- Retinal Differentiation.- Molecular Control of Cell Diversification in the Vertebrate Retina.- Cell Fate Specification in the Drosophila Retina.- Roles of the Extracellular Matrix in Retinal Development and Maintenance.- Adhesive Events in Retinal Development and Function: The Role of Integrin Receptors.- Formation of Neural Pathways for Vision.- Connecting the Eye with the Brain: The Formation of the Retinotectal Pathway.- Regeneration.- Regeneration of the Lens in Amphibians.- How the Neural Retina Regenerates.- Genetic Models.- Mouse Mutants for Eye Development.- Genetic Analysis of Eye Development in Zebrafish.

Textul de pe ultima copertă

The power of molecular genetics has recently returned the discipline of Developmental Biology to its original position at the forefront of biological research. The vertebrate eye was one of the classic embryologic models in the early 1900s. Within the last decade of the 20th century, a return to some of the old questions with the new approaches has put eye development back into the limelight. This book provides an up-to-date and comprehensive overview of the field. The latest advances in delineating genetic hierarchies for eye development in animals are discussed, as well as their relationship to congenital disorders of the eye which affect humans. Since studies in Drosophila have provided significant insight, chapters on this invertebrate model are included. In addition, a number of related areas are discussed which are unique to this book: developmental anatomy of the eye from the perspective of its optical function, recent advances in understanding how the retina connects to the brain, the role of extracellular matrix and cell adhesion molecules in eye development, and two chapters on eye regeneration in amphibians and fish.

Caracteristici

This book gives a comprehensive overview of the development and molecular biology of the vertebrate eye. Includes supplementary material: sn.pub/extras