V monografii opisano techenie perinatal'noy VICh-infektsii po rezul'tatam sobstvennogo mnogoletnego nablyudeniya detey. Podrobno dana kharakteristika klinicheskikh proyavleniy opportunisticheskikh i neopportunisticheskikh zabolevaniy pri VICh-infektsii v detskom vozraste; pokazano eye vliyanie na fizicheskoe i nervno-psikhicheskoe razvitie, rezistentnost' i funktsional'noe sostoyanie organizma patsientov. V rezul'tate klinicheskikh, immunologicheskikh i virusologicheskikh sopostavleniy privedeny tempy progressirovaniya VICh-infektsii u detey pri perinatal'nom infitsirovanii. Predstavlen dinamicheskiy analiz sostoyaniya zdorov'ya detey, klinicheskikh proyavleniy VICh-infektsii, immunologicheskikh parametrov na fone kompleksnoy programmy lecheniya. Pokazany zakonomernosti kletochnogo i gumoral'nogo zven'ev immuniteta, nekotorykh interleykinov. Izdanie predstavlyaet interes dlya pediatrov, infektsionistov, ftiziatrov, immunologov i vsekh spetsialistov, okazyvayushchikh pomoshch' detyam s VICh-infektsiey.