This book primarily focuses on the elucidation of the mechanism as well as diagnosis of viral hepatitis. There is a wide range of issues related to viral hepatitis studies which need to be dealt with. These include treatment, molecular biology of viruses, epidemiology, laboratory diagnostics, etc. Consequently, a diverse range of special textbooks and monographs have been published on this subject. Considering this fact and the rapid growth in our cognizance of the problem, this book emphasizes on some of the most crucial aspects related to the problem of immune pathogenesis of parenterally transmitted viral hepatitis and some aspects of hepatitis diagnostics. Several groups of researchers have shared vital information and results of studies through this book for the reference of specialists working in the field and readers keen on learning about viral hepatitis. Bruce A. Beutler and Jules A. Hoffmann were awarded by The Nobel Prize Committee (in the field of physiology and medicine, 2011) for their discoveries regarding the activation of innate immunity while Ralph M. Steinman was awarded the same for his discovery of the dendritic cell and its role in adaptive immunity. This book is updated with these discoveries and elucidates the challenges posed by inborn and adaptive immune response in case of viral hepatitis.