Viral Polymerases: Structures, Functions and Roles as Antiviral Drug Targets
Editat de Satya Prakash Guptaen Limba Engleză Paperback – 31 oct 2018
- Provides comprehensive, state-of-the-art coverage on virus infections, the virus lifecycle, and mechanisms of polymerase inhibition
- Analyzes the structure-activity relationships of inhibitors of each viral polymerase
- Presents a consistent and comprehensive coverage of all aspects of viral polymerases, including structure, function and their role as antiviral drug targets
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Specificații
ISBN-13: 9780128154229
ISBN-10: 0128154225
Pagini: 496
Dimensiuni: 152 x 229 mm
Editura: ELSEVIER SCIENCE
ISBN-10: 0128154225
Pagini: 496
Dimensiuni: 152 x 229 mm
Editura: ELSEVIER SCIENCE
Public țintă
Clinicians,researchers and academics in Virology, Microbiology/Immunology, medicinal chemistry,drug design, biochemistry, enzyme chemistry, molecular biologyCuprins
1. RNA-Dependent RNA Polymerases and Their Emerging Roles in Antiviral Therapy 2. Structure-Function Relationship of Negative-Stranded Viral RNA Polymerases: Prospectives for Antiviral Therapy 3. RNA-Dependent RNA Polymerase of Alphaviruses: A Potential Target for the Design of Drugs Against Alphaviruses 4. DNA-dependent DNA Polymerases as Drug Targets in Herpesviruses and Poxviruses 5. Polio Virus Polymerase: An Effective Target for Design and Development of Anti-polio Drugs 6. Studies on HIV-1 Polymerase and its Inhibitors 7. Adenovirus DNA Polymerase: Structure, Function and Prospects in Diagnostics and Therapeutics 8. Hepatitis C Virus NS5B RNA-Dependent RNA Polymerase: An Integral Part of HCV Antiviral Therapy 9. HBV Polymerase as a Target for Development of Anti-HBV Drugs 10. Polymerases of Coronaviruses: Structure, Function and Inhibitors 11. Rhinovirus RNA Polymerase: Structure, Function, and Inhibitors 12. Herpes Virus Polymerase Inhibitors 13. Zika Virus Polymerase: Structure, Function and Inhibitors 14. Dengue Virus Polymerase: A Crucial Target for Anti-Viral Drug Discovery 15. Adenovirus DNA Polymerase: Structure, Function and Prospects in Diagnostics and Therapeutics