Cantitate/Preț
Produs

Viral Polymerases: Structures, Functions and Roles as Antiviral Drug Targets

Editat de Satya Prakash Gupta
en Limba Engleză Paperback – 31 oct 2018
Viral Polymerases: Structures, Functions and Roles as Antiviral Drug Targets presents in-depth study information on the structure and functions of polymerases and their roles in the lifecycle of viruses, and as drug targets. Viral polymerases constitute a vital component in the lifecycle of many viruses, such as human immunodeficiency virus (HIV), hepatitis viruses, influenza virus, and several others. They are essentially required for the replication of viruses. Thus, the polymerases that can be found in viruses (called viral polymerases) represent favorable targets for the design and development of antiviral drugs.


  • Provides comprehensive, state-of-the-art coverage on virus infections, the virus lifecycle, and mechanisms of polymerase inhibition
  • Analyzes the structure-activity relationships of inhibitors of each viral polymerase
  • Presents a consistent and comprehensive coverage of all aspects of viral polymerases, including structure, function and their role as antiviral drug targets
Citește tot Restrânge

Preț: 69008 lei

Preț vechi: 94182 lei
-27% Nou

Puncte Express: 1035

Preț estimativ în valută:
13207 13718$ 10970£

Carte tipărită la comandă

Livrare economică 27 ianuarie-10 februarie 25

Preluare comenzi: 021 569.72.76

Specificații

ISBN-13: 9780128154229
ISBN-10: 0128154225
Pagini: 496
Dimensiuni: 152 x 229 mm
Editura: ELSEVIER SCIENCE

Public țintă

Clinicians,researchers and academics in Virology, Microbiology/Immunology, medicinal chemistry,drug design, biochemistry, enzyme chemistry, molecular biology

Cuprins

1. RNA-Dependent RNA Polymerases and Their Emerging Roles in Antiviral Therapy 2. Structure-Function Relationship of Negative-Stranded Viral RNA Polymerases: Prospectives for Antiviral Therapy 3. RNA-Dependent RNA Polymerase of Alphaviruses: A Potential Target for the Design of Drugs Against Alphaviruses 4. DNA-dependent DNA Polymerases as Drug Targets in Herpesviruses and Poxviruses 5. Polio Virus Polymerase: An Effective Target for Design and Development of Anti-polio Drugs 6. Studies on HIV-1 Polymerase and its Inhibitors 7. Adenovirus DNA Polymerase: Structure, Function and Prospects in Diagnostics and Therapeutics 8. Hepatitis C Virus NS5B RNA-Dependent RNA Polymerase: An Integral Part of HCV Antiviral Therapy 9. HBV Polymerase as a Target for Development of Anti-HBV Drugs 10. Polymerases of Coronaviruses: Structure, Function and Inhibitors 11. Rhinovirus RNA Polymerase: Structure, Function, and Inhibitors 12. Herpes Virus Polymerase Inhibitors 13.  Zika Virus Polymerase: Structure, Function and Inhibitors 14. Dengue Virus Polymerase: A Crucial Target for Anti-Viral Drug Discovery 15. Adenovirus DNA Polymerase: Structure, Function and Prospects in Diagnostics and Therapeutics