Applications of Web 2.0 can increasingly be found in the everyday work of professionals of the middle qualification level. For the competent handling of the new media certain skills are also required: thus, employees need to communicate more, they need to learn to deal with customer evaluations, they need to work interdiscplinarily and interculturally and furthermore, they need to know the legal limitations. This publication presents fields of work and areas, where professionals today are already affected by the qualification requirements within the context of Web 2.0 applications and shows the challenges of this topic for various educational areas.