Most "mysterious" diseases are caused by an insidious strain of a microbe commonly found in the oral area in an usually harmless form, a "green-producing" non-hemolytic alpha streptococcus, which acquires pathogenicity in oral infections and spreads elsewhere in the body. This volume discusses the monumental works of E.C.Rosenow MD et al. and implications and incorporating reference to historical foundations and modern perspectives, including the likes of so-called "auto-immunity" and AIDS-HIV issues. Rosenow's documentation of benefits of specific vaccine and antibody, beyond the well-documented role of inciting oral infections, speaks volumes - and points the way to a grand future for medical science.