The World Drug Report aims to improve understanding of the illicit drug problem and contribute to more international cooperation for countering it. The first chapter gives an overview of recent trends and the drug situation in terms of production, trafficking and consumption, and the consequences of illicit drug use in terms of treatment, drug-related diseases and drug-related deaths. The second chapter focuses on New Psychoactive Substances, i.e. psychoactive substances not under international control. It presents emerging trends in the composition, production and distribution, patterns of use and approaches taken by countries in response to the emergence of these substances.