Dr. Marcus Samuels is a medical missionary in Japan, and his life has been God's work despite a severe anxiety disorder. After 12 years, he aches to start his own family life back in the States. Spurred into motion by his mother's sudden illness, he's caught off-guard when he realizes just how much he'll miss Keiko Oichi, a fellow pediatrician at the Children's Christian Mission Hospital. Keiko grew up in the United States as a foreign exchange student. Her conversion to Christ, as well as getting to know Marcus, have radically altered her emotionally-detached acceptance of her traditional Japanese future. When Marcus says he's leaving Japan for good, she feels lost at the prospect of losing him. When Keiko's parents learn of her conversion and feelings for a Christian man, the couple faces a crossroads in love and faith that will change both of their lives irrevocably.