Stomatologicheskaya zabolevaemost' detey rannego vozrasta obuslovlena narusheniyami gisto-, organo- i sistemogeneza v period antenatal'nogo razvitiya, a takzhe vo vremya postnatal'nogo formirovaniya organov chelyustno-litsevoy oblasti. Pri izuchenii kharaktera morfologicheskikh izmeneniy v strukture tkaney zubov vyyavleny tsirkulyatornye narusheniya v spetsializirovannykh kletkakh - odontoblastakh i enameloblastakh. Morfometricheskaya otsenka podtverdila dannye morfologicheskogo issledovaniya, zaklyuchayushchiesya v sosudistykh narusheniyakh, kotorye vliyayut na sinteticheskuyu aktivnost' kambial'nykh kletok pri strukturnoy organizatsii tverdykh tkaney zubov. Dannye ob izmeneniyakh, voznikayushchikh v formiruyushchikhsya tkanyakh organov polosti rta, posluzhili osnovoy dlya planirovaniya lechebno-profilakticheskikh mer u detey na raznykh etapakh formirovaniya prikusa. Predlozhen i realizovan kompleks lecheniya ryada stomatologicheskikh zabolevaniy u detey, perenesshikh neblagopriyatnoe techenie antenatal'nogo perioda razvitiya, kotoryy vklyuchal ortodonticheskie, ortopedicheskie i fizioterapevticheskie metody, pozvolivshie normalizovat' funktsiyu myshts chelyustno-litsevoy oblasti i povysit' rezistentnost' tverdykh tkaney zubov.