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A Guide to Blood and Marrow Transplantation

Autor H. Joachim Deeg, Hans-Georg Klingemann, Gordon L. Phillips, Gary Van Zant
en Limba Engleză Hardback – 19 oct 1998
This completely revised and enlarged 3rd edition continues the idea of the previous version to provide an up-to-date overview of blood and marrow transplantations. Indication to transplantation and pre-transplant considerations are discussed in detail before the transplant procedure with all acute and delayed procedure is described. An outlook on the latest developments and their future aspects is included, and problems and pre- and post-transplant complications are discussed. This book helps practising hematologists, oncologists,and other physicians as well as physicians in training and students to develop an idea as to when blood and marrow transplantation should be considered, what the costs are and how a donor can be selected.
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Specificații

ISBN-13: 9783540625407
ISBN-10: 3540625402
Pagini: 230
Dimensiuni: 155 x 235 mm
Greutate: 0.53 kg
Ediția:Completely Rev
Editura: Springer Verlag
Colecția Springer
Locul publicării:Berlin, Heidelberg, Germany

Public țintă

Professional/practitioner

Cuprins

Introduction.- Pretransplant Considerations. Rationale and Indications for Transplantations.Timing of Transplantation. Stem Cell Sources. Preparation for Stem Cell Transplantation. Cost Considerations.- Transplant Procedure.Conditioning Regimens. Collection and Processing of Stem Cells. In Vitro Expansion of Stem Cells. Genetic Manipulation of Hematopoietic Stem Cells. Prevention and Treatment of Relapse.- Transplant-Related Problems.- Side Effects of Conditioning Regimens. Graft Failure. Graft-Versus-Host Disease. Management of Infections. Single and Multi- Organ Failure. Chronic Graft-Versus-Host Disease. Delayed Complications.- Long-Term Observations. Follow-Up After Discharge from the Transplant Center. Rehabilitation.- Quo Vadis

Descriere

An up-to-date overview of blood and marrow transplantations, the book discusses in detail Indication to transplantation and pre-transplant considerations. An outlook on the latest developments and their future aspects is included, while problems and pre- and post-transplant complications are fully explored.

Textul de pe ultima copertă

This book provides an introduction to marrow and peripheral blood stem cell transplantation (including cord blood transplants), emphasizing the principles of this rapidly evolving area. A brief historical perspective is given and the latest developments are discussed. Particular attention is given to the rationale and indications for transplantation, the selection of donors and source of stem cells, and the separation, expansion and manipulation of stem cells. Essential aspects of histocompatibility, preparative regimens used in stem cell transplantation, the use of hematopoietic growth factors and cytokines, the pathophysiology of the graft-versus-host reaction, and the management of complications are dealt with. This book should provide the practicing internist, pediatrician, hematologist, and oncologist as well as other physicians in training or in practice, physicians' assistants, nurses, and students with the information necessary to understand the concepts of stem cell transplantation and to include transplantation in the treatment planning soon after a diagnosis has been established. The text should also be useful to the physician who resumes the patients' care when they return from the transplant center.

Caracteristici

Authors from three leading centres in the US