A Guide to Numerical Modelling in Systems Biology: Texts in Computational Science and Engineering, cartea 12
Autor Peter Deuflhard, Susanna Röblitzen Limba Engleză Hardback – 15 iul 2015
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Specificații
ISBN-13: 9783319200583
ISBN-10: 3319200585
Pagini: 150
Ilustrații: X, 168 p. 42 illus., 33 illus. in color.
Dimensiuni: 155 x 235 x 17 mm
Greutate: 0.44 kg
Ediția:1st ed. 2015
Editura: Springer International Publishing
Colecția Springer
Seria Texts in Computational Science and Engineering
Locul publicării:Cham, Switzerland
ISBN-10: 3319200585
Pagini: 150
Ilustrații: X, 168 p. 42 illus., 33 illus. in color.
Dimensiuni: 155 x 235 x 17 mm
Greutate: 0.44 kg
Ediția:1st ed. 2015
Editura: Springer International Publishing
Colecția Springer
Seria Texts in Computational Science and Engineering
Locul publicării:Cham, Switzerland
Public țintă
GraduateCuprins
Preface.- Outline.- ODE Models for Systems Biological Networks.- Numerical Simulation of ODE Models.- Parameter Identification in ODE Models.- Appendix.- Software.- Index.
Recenzii
“This book is structured in three chapters coveringthe ODE modeling for the identification and characterization of biologicalnetworks, the handling of numerical simulations for the proposed ODE models andthe corresponding parameters identification, respectively. … included a list ofnumerical algorithms and software packages that facilitate the understanding ofthe ODE-related problems. … written in an accessible manner, with plenty ofexamples, making it a valuable addition to the series of textbooks in computationalscience and engineering.” (Irina Ioana Mohorianu, zbMATH, Vol. 1325.92001, 2016)
“It focuses almost solely on the mundanemathematical topic of ordinary differential equations (ODEs) and theirparameter estimation … . the prime readership for this volume is to be foundmore amongst advanced researchers in systems biology trying to find reasons forunstable results of some ODE simulation or identification packages.” (L.-F. Pau,Computing Reviews, November, 2015)
“It focuses almost solely on the mundanemathematical topic of ordinary differential equations (ODEs) and theirparameter estimation … . the prime readership for this volume is to be foundmore amongst advanced researchers in systems biology trying to find reasons forunstable results of some ODE simulation or identification packages.” (L.-F. Pau,Computing Reviews, November, 2015)
Notă biografică
Peter Deuflhard, founder of ZIB and co-founder of MATHEON in Berlin, has written successful books in numerical analysis and scientific computing (three of them with Springer).
Susanna Röblitz is Head of the research group Computational Systems Biology at ZIB and professor for Applied Mathematics and Bioinformatics at FU Berlin.
Textul de pe ultima copertă
This book is intended for students of computational systems biology with only a limited background in mathematics. Typical books on systems biology merely mention algorithmic approaches, but without offering a deeper understanding. On the other hand, mathematical books are typically unreadable for computational biologists. The authors of the present book have worked hard to fill this gap. The result is not a book on systems biology, but on computational methods in systems biology. This book originated from courses taught by the authors at Freie Universität Berlin. The guiding idea of the courses was to convey those mathematical insights that are indispensable for systems biology, teaching the necessary mathematical prerequisites by means of many illustrative examples and without any theorems. The three chapters cover the mathematical modelling of biochemical and physiological processes, numerical simulation of the dynamics of biological networks, and identification of model parameters by means of comparisons with real data. Throughout the text, the strengths and weaknesses of numerical algorithms with respect to various systems biological issues are discussed. Web addresses for downloading the corresponding software are also included.
Caracteristici
Mathematics without theorems in clear orientation towards systems biology Many illustrative examples to explain details Guide to software indicating its strengths and weaknesses Includes supplementary material: sn.pub/extras