This report summarizes the results of a foundational study undertaken in support of NHTSA to identify the research needs and priorities in the near-, mid-, and long-term, as well as the challenges and opportunities to the development and commercial deployment of light-weight, plastics-rich, and fuel efficient vehicles by 2020 that would be designed to comply with all applicable crash safety standards and regulatory requirements. The Volpe Center reviewed relevant literature, interviewed subject matter experts and ongoing research, developed a PCIV 2020 Safety Vision, and identified the major R&D needs, challenges, and opportunities to develop a roadmap for PCIV safety.