The editors and authors of this textbook introduce the relatively new subject of “academic and educational entrepreneurship” from a holistic viewpoint. Following a structured approach suitable for the classroom, the book opens with a concise introduction to the theories and schools of thoughts in the context of academic and educational entrepreneurship. It then reveals seven scientifically developed key aspects (including sustainability, internationalization, and cultural components) in order to be a successful academic and educational entrepreneur. After the theoretical background, the authors, who are the doyens of academic and educational entrepreneurship, share their insights and professional experiences with the readers by demonstrating the impact and relevance of the theoretical concepts to the actual entrepreneurial experience.