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ADARs: Methods in Enzymology, cartea 710

Peter Beal
en Limba Engleză Hardback – 27 ian 2025
ADARs, Volume 710 in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Updates in this new release include Yeast as a discovery tool for hyperactive ADARs, X-ray crystallography of ADAR-RNA complexes, Enrichment capture enhances the ability to detect A-to-I editing, Editing specificity of ADAR isoforms, Novel chemical tools for detection methods of A to I sites, En Masse Evaluation of RNA Guides (EMERGe) for ADARs, Mouse models for defining physiological functions of ADARs, Nanopore sequencing to detect A-to-I editing sites, CellREADR: An ADAR-based RNA sensor, and more.

Additional sections cover Site-directed RNA editing with MS2-ADAR systems, Sequencing and Bioinformatic Tools for Accurate Assessment of A to I editing in Complete Transcriptomes, Aptazyme-directed A to I RNA editing, and Obstacles in quantifying A-to-I editing by Sanger Sequencing.

  • Provides the latest information on ADARs research
  • Offers outstanding, original reviews on a range of ADARs research topics
  • Serves as an indispensable reference for researchers and students alike
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Specificații

ISBN-13: 9780443315848
ISBN-10: 0443315841
Pagini: 322
Dimensiuni: 152 x 229 mm
Editura: ELSEVIER SCIENCE
Seria Methods in Enzymology


Cuprins

1. Yeast as a discovery tool for hyperactive ADARs
Shay Ben-Aroya and Erez Levanon
2. X-ray crystallography of ADAR-RNA complexes
Andrew Fisher
3. Enrichment capture enhances the ability to detect A-to-I editing
Heather A. Hundley
4. Editing specificity of ADAR isoforms
Michael F. Jantsch
5. Novel chemical tools for detection methods of A to I sites
Jennifer Heemstra
6. En Masse Evaluation of RNA Guides (EMERGe) for ADARs
Peter Beal
7. Mouse models for defining physiological functions of ADARs
Carl Walkley
8. Nanopore sequencing to detect A-to-I editing sites
Meng How Tan
9. CellREADR: An ADAR-based RNA sensor
Z. Josh Huang
10. Site-directed RNA editing with MS2-ADAR systems
Toshifumi Tsukahara
11. Sequencing and Bioinformatic Tools for Accurate Assessment of A to I editing in Complete Transcriptomes
Eli Eisenberg
12. Aptazyme-directed A to I RNA editing
Zhuo Tang
13. Obstacles in quantifying A-to-I editing by Sanger Sequencing
Ayelet Lamm